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Results for "

interferon a-1/13

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
  • Recombinant Protein
    5
    TargetMol | Recombinant_Protein
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    TargetMol | Antibody_Products
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IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)
LeIF D, Interferon α-D, Interferon α-1 13, Interferon α1, Interferon alpha-D, Interferon alpha-1 13, Interferon alpha 1, IFN-α-1 13, IFN-α-1, IFNα1, IFN-alpha-1 13, IFN-alpha-1, IFNalpha 1, IFNA1, IFN α1, IFN α 1, IFN alpha1
TMPK-00074
IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. IFN-alpha 1 IFNA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 45.88 kDa and the accession number is P01572.
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7-10 days
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QTY
SPR-compatible buffer
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IL-18 Protein, Mouse, Recombinant (His)
Interferon γ-inducing factor, Interleukin-1 gamma, Igif, IL-1 gamma, Interleukin-1 γ, IL-1 γ, Interferon gamma-inducing factor, Il18, IFN-γ-inducing factor, IFN-gamma-inducing factor, Interleukin-18
TMPJ-01056
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins and virally encoded IL-18BP homologs. It augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. In the presence of IL-12 or IL-15, IL-18 enhances anti-viral Th1 immune responses by inducing IFN-gamma production and the cytolytic activity of CD8+ T cells and NK cells. In the absence of IL-12 or IL-15, however, IL-18 promotes production of the Th2 cytokines IL-4 and IL-13 by CD4+ T cells and basophils.
  • Inquiry Price
7-10 days
Size
QTY
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Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)
interferon, α1, interferon, alpha 1, Interferon α1, IFN-αD, IFN-α, IFN-alphaD, IFN-ALPHA, IFNA13, IFNA@, IFN, IFL
TMPY-04578
Interferon alpha 1 IFNA1 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 20.8 kDa and the accession number is L0N195.
  • Inquiry Price
7-10 days
Size
QTY
SPR-compatible buffer