hypothalamic peptide

This human neuropeptide of the RFamide peptide family with orexigenic activity may be also involved in the control of feeding behavior. The 26RFa gene is exclusively expressed in the ventromedial hypothalamic nucleus and in the lateral hypothalamic area.

Oxytocin acetate (α-Hypophamine acetate) is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.

CART(62-76)(human,rat) TFA, a neuropeptide encompassing residues 62-76 of the CART peptide, exhibits neurotransmitter-like properties and modulates the striatal noradrenergic system, as well as the corticostriatal and hypothalamic serotoninergic (5-HT) systems in the rat brain [1].

Exendin-4 (3-39) is a truncated peptide variant of Exendin-4, missing the initial two amino acids, and serves as a potent agonist for the Glucagon-like peptide-1 receptor (GLP-1r). This compound, along with Exendin-4, is utilized in the study of diabetes and hypothalamic-pituitary-adrenal (HPA) axis disorders [1] [2].

Alarin (human) is a hypothalamic neuropeptide from the galanin peptide family that comprises the signal sequence of the GALP precursor and the initial five amino acids (aa) of the mature GALP [1].

Vasopressin (argipressin), a cyclic nine-peptide synthesized by hypothalamic neurons, is one of the hormones involved in peptide prohormone synthesis. Vasopressin is involved in the regulation process of hypothalamic-pituitary-adrenal axis, increasing the amount of solute free water reabsorbed from the renal tubule's colate back into the circulation, narrowing arteries to increase pressure, enhancing the stimulating effect of corticotropin releasing factor to regulate pituitary corticotropin secretion. Vasopressin acts as a neurotransmitter during nerve conduction by binding to specific G-protein-coupled receptors.

ACTH (1-13) is a 13-aa peptide with cytoprotective effects in a model of ethanol-induced gastric lesions in rats. Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland and plays a critical role in the hypothalamic-pituitary-adrenal axis in response to biological stress.

[Gln8] Luteinizing hormone releasing hormone ([Gln8] LH-RH), Avian hypothalamic peptide that stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.

[Gln8]-C517 (LH-RH), chicken acetate is an avian hypothalamic peptide that stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.