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(11)
By Target- Topoisomerase
- Apoptosis(4)
- ADC Cytotoxin(3)
- Antibody-Drug Conjugates (ADCs)(2)
- Autophagy(2)
- HIV Protease(2)
- Mitophagy(2)
- NF-κB(2)
- AMPK(1)
- Others(3)
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Results for "
human topoisomerase i
" in TargetMol Product Catalog- Inhibitors & Agonists17
- Inhibitory Antibodies2
- PROTAC Products1
- Natural Products6
- Isotope Products1
- Disease Modeling1
Trastuzumab deruxtecan
VRN-101099, T-DXd, DS-8201a, DS 8201
T366461826843-81-5
Trastuzumab deruxtecan (T-DXd) is an antibody-active molecule conjugate (ADC) with anticancer and antitumor activity, which is composed of a monoclonal antibody targeting human epidermal growth factor receptor 2 (HER2) coupled to a topoisomerase I inhibitor (DXd). Trastuzumab deruxtecan has an improved effect on the treatment of HER2-positive breast cancer and gastric cancer.
- $521
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Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38
T9901A-1017
Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 is an antibody-drug conjugate (ADC) composed of the human anti-CCL2 (chemokine ligand 2) antibody Carlumab, connected via the Mc-VC-PAB linker to the topoisomerase I inhibitor SN38. The toxic component and linker of the ADC is Mc-VC-PAB-SN38. This ADC is employed in cancer research studies.
- Inquiry Price
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