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hpde4

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
Cilomilast
SB-207499, Ariflo
T6445153259-65-5
Cilomilast (SB-207499) is a potent PDE4 inhibitor with an IC50 of approximately 110 nM, demonstrating anti-inflammatory activity and minimal central nervous system effects. Phase 3.
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NPD-001
NPD001,NPD 001
T24544469863-16-9
NPD-001 is an effective inhibitor of TbrPDEB1. NPD-001 is 10-fold more potent on hPDE4 (hPDE4B1 IC50 = 0.6 nM) than on TbrPDEB1 (IC50 = 4 nM).
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6-8 weeks
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