hel-s 106

Expression system: HEK293 Cells
Length: 1-519, Full Length
Activity: Not Tested

LAP is a highly efficient and biocompatible radical photoinitiator used to initiate radical chain polymerisation and synthesise polymeric materials under light irradiation. The primary wavelength for light absorption and polymerisation initiation is 405 nm. LAP concentrations ≥3.4 mmol/L and the radicals it generates exhibit cytotoxicity towards M-1 mouse renal collecting duct cells.

Expression system: HEK293 Cells
Length: 279-390, Partial
Activity: ELISA、Cells

Expression system: HEK293 Cells
Length: 30-278 (mutation), Partial
Activity: Cells Activity

Expression system: HEK293 Cells
Length: 30-390 & 279-390, Full Length
Activity: ELISA

Expression system: HEK293 Cells
Length: 301-412 (mutation), Partial
Activity: Cells Activity

Expression system: HEK293 Cells
Length: 1-390, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-381, Full Length
Activity: Not Tested

Lupus autoantigen peptide (LAP), a derivative of the autoantigen La found in systemic lupus erythematosus (SLE) patients, spans amino acids 11-28 of La and functions as an antiviral peptide. It primarily blocks the hepatitis C virus (HCV) from interacting with internal ribosome entry site (IRES) trans-acting factors (ITAFs), notably the polypyrimidine tract-binding protein (PTB) and poly(rC)-binding protein 2 (PCBP2). In a Huh7 cell-based reporter assay, LAP at a concentration of 60 µM effectively hampers HCV IRES-mediated translation, a process reversible by adding recombinant forms of PTB and PCBP2.