harmine

Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.

Harmine hydrochloride (telepathine hydrochloride) is extracted from Peganum Harmala Genus.

Harmine 19a is an antitumor agent based on the structure of the Twist1 inhibitor harmine. It exhibits inhibitory activity against A549 and H2228 cell lines, with IC50 values of 2.03 μM and 9.80 μM respectively, and can be utilized for non - small cell lung cancer (NSCLC).

Tetrahydroharmine (Leptaflorine) is a natural product found in the stems and large branches of Banisteriopsis caapi cultivar Da Vine. Tetrahydroharmine is a Monoamine oxidase A inhibitor.

Norharmine is an analogue of harman and functions as an alkaloid. It serves as an inhibitor of both monoamine oxidase A (MAO-A) and DYRK1A. While it exhibits weak inhibitory activity against MAO-A, it has certain inhibitory effects on DYRK1A.

Harmaline hydrochloride (Harmidine hydrochloride) is a fluorescent indole alkaloid from the group of harmala alkaloids and beta-carbolines. It is the partially hydrogenated form of harmine.Harmaline produces a generalized tremor in normal rats by inducing rhythmic firing of inferior olivary neurons

HL22 is a derivative of harmine. It exhibits significant inhibitory effects on three cancer cell lines: HCT116, MGC803, and MCF7. Moreover, HL22 can impede the migration and colony formation of MGC803 cells. Its anticancer mechanism is associated with multiple metabolic pathways and can be utilized for tumor research.

Harmaline is a fluorescent psychoactive indole alkaloid from the group of harmala alkaloids and beta-carbolines. It is the reduced hydrogenated form of harmine.

Lon 954, also known as Harmine, is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds.

Antitumor agent-49 (Compound 10), a harmine derivative-furoxan hybrid featuring nitric oxide (NO) donating properties, exhibits cytotoxic effects against HepG2 cells, achieving an IC50 value of 1.79 µM and inducing significant NO production in vitro [1].