ga 3

GA3-AM is a cell-permeable chemical dimerizer.

PLGA-PEG-PLGA (hydrogel) (LA:GA 3:1) (15% solution) is a biodegradable thermosensitive hydrogel that undergoes phase transition at specific temperatures. It is widely applicable in drug delivery systems, tissue engineering, wound dressings, and biosensors.

PLGA-PEG-PLGA (LA:GA 3:1) (20% solution) is a biodegradable and thermosensitive hydrogel that undergoes phase transition at specific temperatures. PLGA-PEG-PLGA (hydrogel) (LA:GA 3:1) (20% solution) is widely utilized in delivery system development, tissue engineering, wound dressing research, and biosensor applications. The physicochemical characteristics of PLGA-PEG-PLGA (hydrogel) (LA:GA 3:1) (20% solution) support extensive investigation in biomaterials science and regenerative medicine research.

PLGA-PEG-PLGA (hydrogel) (LA:GA 3:1) is a biodegradable, thermosensitive hydrogel that undergoes phase transition at a specific temperature. It is widely used in drug delivery systems, tissue engineering, wound dressings, and biosensors.

Gibberellic acid (GA3) is a hormone found in plants and fungi.

Gibberellins-BSA is a hapten-carrier protein conjugate formed by coupling Gibberellins to bovine serum albumin (BSA). As a hapten, Gibberellins alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity. Gibberellins-BSA may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M TBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

Mizagliflozin is an orally active, selective SGLT1 inhibitor with a Ki value of 27 nM for human SGLT1. Mizagliflozin is 303 times more selective for SGLT1 than for SGLT2. Mizagliflozin is an anti-diabetic drug that can improve postprandial blood sugar fluctuations and may have the potential to improve chronic constipation.

Prostaglandin A3 is a non-enzymatic dehydration product of prostaglandin E3 (PGE3). It demonstrates significant affinity for canine EP2 and EP4 receptors with IC50 values of 120 nM and 20 nM, respectively. For human PPARγ, Prostaglandin A3 has a Ki value of 188 μM.

Patidegip, laos known as Saridegib and IPI-926, is an orally bioavailable, cyclopamine-derived (for structure comparison see Fig 1) inhibitor of the Hedgehog (Hh) pathway with potential antineoplastic activity. Specifically, Hedgehog pathway inhibitor IPI-926 binds to and inhibits the cell membrane-spanning G-protein coupled receptor SMO, which may result in the suppression of Hh pathway signaling and a decrease in tumor cell proliferation and survival. SMO is activated upon binding of Hh ligand to the cell surface receptor Patched (PTCH); inappropriate activation of Hh signaling and uncontrolled cellular proliferation may be associated with SMO mutations.

omega-3 Arachidonic acid ethyl ester is a polyunsaturated fatty acid suitable for biochemical experiments and drug synthesis research.

GA32 (compound 58r) is a potent androgen receptor (AR)/glucocorticoid receptor (GR) dual inhibitor with IC50 values of 0.13 μM and 0.83 μM for AR and GR, respectively. GA32 inhibits the proliferation of Enzalutamide-resistant, castration-resistant prostate cancer both in vitro and in vivo [1].

SGA360 is a selective aryl hydrocarbon (Ah) receptor modulator. It exhibits anti-inflammatory properties.

PLGA3000-PEG1000-VS (PLGA3000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Such polymers are valuable for drug delivery research due to their ability to self-assemble into discrete aggregates.

PLGA3000-PEG2000-VS (PLGA3000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Due to its ability to self-assemble into discrete aggregates, this type of polymer is utilized in research focused on drug delivery.

PLGA3000-PEG3000-VS (PLGA3000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Due to its ability to self-assemble into distinct aggregates, this type of polymer is useful in drug delivery research.

PLGA3000-PEG5000-VS (PLGA3000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers are utilized in drug delivery research due to their ability to self-assemble into distinct aggregates.

PLGA38000-PEG10000 is an amphiphilic polymer. Due to its ability to self-assemble into discrete aggregates, this type of amphiphilic polymer is useful for research in drug delivery.

Trifloxystrobin metabolite CGA-321113 (Standard) is a standard material used for research and analysis of Trifloxystrobin metabolite CGA-321113. It is an acid metabolite of the fungicide trifloxystrobin with antifungal activity.

Omega-3 Arachidonic Acid methyl ester, primarily represented by docosahexaenoic acid, eicosapentaenoic acid, and α-linolenic acid, is an essential dietary nutrient crucial for normal growth and development. It is the neutral, fat-soluble form of the rare fatty acid, ω-3 Arachidonic Acid. The ω-3 fatty acids group is associated with reduced inflammation and autoimmune activity, as well as decreased thrombosis and platelet activation.

(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) is one of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency. The gallate group causes current block, as evident by brief downward current transitions.

18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), is a potent inhibitor of type 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) with an IC50 value of 0.10 µM in rat kidney microsome assays. This compound is a substrate for organic anion transporters (OAT) 1 and OAT3, exhibits anti-inflammatory properties, and holds potential for research into pseudohyperaldosteronism [1] [2].

(-)-Epicatechin gallate (Standard) is a reference standard for research and analysis in studies involving (-)-Epicatechin gallate. (-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) is one of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency. The gallate group causes current block, as evident by brief downward current transitions.

Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that binds complement component 3 (C3) and its activation fragment C3b. Pegcetacoplan acetate is utilized in biomedical research focused on complement cascade regulation, complement-mediated disease modeling, and C3-dependent immune activation pathways in systems including age-related macular degeneration, C3 glomerulopathy, geographic atrophy, and autoimmune hemolytic anemia.