fascin

NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.

Imipramine (Dimipressin) is an orally active Fascin1 inhibitor with antidepressant and antitumor activity.Imipramine inhibits the 5-hydroxytryptamine transporter (IC50: 32 nM), induces apoptosis, and induces autophagy in U-87MG glioma cells.Imipramine has neuroprotective and immunomodulatory activities, inhibits TNT, and is used to label brain blood vessels.Imipramine is a neuroprotective and immunomodulatory compound. Imipramine has neuroprotective and immunomodulatory activities, inhibits invasion and migration of TNBC cells, and can be used to study breast cancer and epilepsy.

BDP-13176 is a potent inhibitor of fascin 1(Kd of 90 nM and an IC50 of 240 nM). It has potential as an anti-metastatic agent

Z17544625 is a potent Fascin inhibitor with a strong binding affinity to Fascin, effectively inhibiting Actin bundling. It significantly reduces the proliferation and migration of colorectal cancer (CRC) cells. This compound is applicable in cancer research, particularly for studying colorectal cancer (CRC).

Z118298144 is a Fascin inhibitor that binds strongly to Fascin, effectively inhibiting Actin bundling. This compound significantly reduces the proliferation of colorectal cancer (CRC) cells and impedes their migration, making it valuable for cancer research, particularly in studies related to colorectal cancer (CRC).