enterovirus 71

MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.

Anti-Enterovirus 71 VP4 Antibody (3E202) is a monoclonal antibody targeting EV71 (Enterovirus 71) VP4, which is a mouse-derived antibody.

Rupintrivir (AG7088) is an antiviral agent and an irreversible inhibitor targeting human rhinovirus 3C protease (EC50 = 0.023 μM), featuring high selectivity and immunomodulatory activity, capable of effectively inhibiting multiple HRV serotypes as well as EV71 and EV-D68 replication, commonly used for research on viral infection mechanisms.

1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastric accommodation. 3. Corydaline exhibits the anti-acetylcholinesterase, antiallergic, and antinociceptive activities. 4. Corydaline has potent inhibition of CYP2C19 and CYP2C9.

Norwogonin (5,7,8-Trihydroxyflavone), isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).

DC07090 Dihydrochloride is a potent inhibitor of human enterovirus 71 3C protease.

DC 07090 is a human enterovirus 71 3C protease inhibitor with antiviral activity for the study of nucleic acid virus infections.

Vapendavir is a potent enteroviral capsid binder. Vapendavir has an effective antiviral activity for enterovirus 71 replication (EC50: 0.5-1.4 μM in different EV71 strains).

Antiviralagent 71 (Compound 26) is a potent antiviral agent exhibiting broad-spectrum activity against enteroviruses such as EV-D68, Echo-11, and HRV-14, with an EC50 ranging from 0.017 to 4.1 μM. Antiviralagent 71 is utilized in research related to non-polio enterovirus (NPEV) infections.

Methyl 3,4-Dihydroxyphenylacetate is an effective enterovirus 71 (EV71) inhibitor capable of suppressing EV71 replication in rhabdomyosarcoma (RD) cells, exhibiting antiviral activity.

DMA-135 hydrochloride (DMA-135 HCl) Antivirally active compounds that target RNA and inhibit enterovirus type 71 (EV71) IRES-dependent translation and replication.DMA-135 hydrochloride can be used in the study of enteroviral infections.

Antiviral Agent 23, an effective inhibitor of enterovirus 71 (EV71) with an EC50 value of 94 nM, also exhibits potent suppression of METTL3/METTL14 activity. This compound is employed in the research of infections.

7-Hydroxyisoflavone against Enterovirus 71 in vitro.

ZHSI-1 is an EV71 (Enterovirus 71) inhibitor that blocks EV71/CVA16 replication and virus-induced pyroptosis linked to viral pathogenesis. It effectively prevents EV71 infection in neonatal and young mice in animal models and can be used to study viral infections such as hand, foot, and mouth disease (HFMD) [1].