dutp

dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.

AA-dUTP [sodium salt] is a fluorescent dye used for staining cDNA.

5-PA-dUTP (5-Propargylamino-dUTP) is a modified nucleotide with a C5 modification, designed for incorporation into DNA nanoparticles (DNPs) to facilitate efficient delivery of photosensitizers.

5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule utilized in DNA synthesis and sequencing.

dUTP (Deoxyuridine triphosphate) is a deoxyuridine phosphate featuring a triphosphate group at the 5' position. It can be utilized in PCR reactions.

5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of dUTP nucleotidohydrolase (dUTPase) in E. coli with a Ki greater than 1 mM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis.

BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase. It exhibits outstanding selectivity for varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1) owing to its phosphorylation by the virus-specific thymidine kinase.

Rp-2'-Deoxyuridine-5'-O-(1-thiotriphosphate) (Rp-dUTP-α-S), a sulfur-containing nucleotide isomer and purinergic P2Y2 receptor agonist, preferentially promotes inositol phosphate accumulation in 1321N1 astrocytoma cells with P2Y2 receptors (EC50 = 12.5 µM) compared to those expressing P2Y4 receptors at a concentration of 10 µM.

Tetramethylrhodamine-dUTP (TAMRA-dUTP) is utilized for DNA end-labeling [1].

5-Propargylamino-3'-azidomethyl-dUTP sodium is the sodium salt form of 5-Propargylamino-3'-azidomethyl-dUTP. This compound is a biotinylated modified nucleotide useful for applications in DNA synthesis and sequencing.

Rp-dUTPαS (tetrasodium) is an isomer of the sulfur-containing nucleotide dUTP-α-S and acts as an agonist of the purinergic P2Y2 receptor. It selectively induces the accumulation of inositol phosphates in P2Y2-expressing 1321N1 cells with an EC50 of 12.5 μM.

dUTP sodium (sodium 2'-deoxyuridine 5'-triphosphate) is utilized for PCR (Polymerase Chain Reaction).

Sp-dUTPαS tetrasodium is an isomer of the sulfur-containing nucleotide dUTPαS.

5-BrdUTP sodium salt is a TdT substrate used for labeling DNA double-strand breaks.

ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) is a selective inhibitor of HIV and AMV reverse transcriptases, with Ki values of 0.05 µM for HIV and 1 µM for AMV. It is preferentially incorporated at dTTP sites within the DNA strand, thereby preventing further chain elongation [1].

ddUTP (lithium), at a concentration of 100mM in H20, serves as a nucleotide analog capable of being integrated into DNA, RNA, or other nucleic acids. It is applicable in DNA/RNA hybridization experiments including Southern and Northern blots.

5-Propargylamino-ddUTP triethylamine (100mM in water) is a reagent used in biochemical reactions.

5-Propargylamino-ddUTP sodium (100mM in water) is a reagent used in biochemical reactions.

5-CF3-ddUTP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

TAS-114 is an orally active dual inhibitor of dUTPase and dihydropyrimidine dehydrogenase (DPD). TAS-114 targets the intercellular metabolism of 5-FU to enhance antitumor activity and modulates catabolic pathways to improve the systemic availability of 5-FU.

2',3'-Dideoxyuridine-5'-O-(1-thiotriphosphate) (ddUTPαS) tetrasodium is a sulfur-containing nucleoside triphosphate derivative.

3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II and strongly competes with UTP incorporation into RNA, with a Ki value of 2.0 μM[1].

'3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II by competitively blocking UTP incorporation into RNA with a dissociation constant (Ki) of 2.0 μM[1].