dns

DNS-8254 is a potent and selective Phosphodiesterase 2 (PDE2) inhibitor for the treatment of Memory Disorders (hPDE2a IC50 = 8 nM, Rat Cl-int = 25.6 uL/min/mg). DNS-8254 demonstrated significant memory enhancing effects in a rat model of novel object reco

Dinalbuphine sebacate is a long-lasting prodrug of nalbuphine, acting as a moderate-efficacy partial agonist or antagonist of the μ-opioid receptor and as a high-efficacy partial agonist of the κ-opioid receptor.

Dansyl glutathione is a fluorescent trapping agent and a dansyl-labeled glutathione derivative. it enhances LC-MS/MS sensitivity for reactive metabolite identification in toxicity screening.

Dansylleucine is an agent of bioactive chemical.

Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity. Its potency is similar to propranolol. Bupranolol is quickly and completely absorbed from the gut. Over 90% undergo first-pass metabolism. Bupranolol has a plasma half life of about two to four hours, with levels never reaching 1 µg/l in therapeutic doses. The main metabolite is carboxybupranolol, 4-chloro-3-[3-(1,1-dimethylethylamino)-2-hydroxy-propyloxy]benzoic acid – that is, the methyl group at the benzene ring is oxidized to a carboxyl group –, of which 88% are eliminated renally within 24 hours.

DNS-pE is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.

Bis(DNS-glutathione) disulfide is a synthetic polypeptide composed of repeating α-L-glutamic acid units. Poly-DNS-glutathione is recognized for its biocompatibility, biodegradability, and non-immunogenic nature, making it highly suitable for advanced drug-delivery system engineering. Bis(DNS-glutathione) disulfide has been extensively employed in the creation of nanomaterials designed to improve drug loading, controlled release, and targeted biodistribution, ultimately supporting the development of safer and more efficient therapeutic delivery platforms.

2-Np-Dnsah-13C6 (Standard) is a reference standard of 2-Np-Dnsah-13C6 intended for quantitative analysis, quality control, and related biochemical research applications.

Glutamic acid, N-stearoyl- is a α-amino acid.

Nifursol is a livestock feed additive and antiobiotic used to prevent the growth of histomonas.

3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) sodium is a type of sialic acid. It protects oligo/(poly)sialic acid chains from the impact of non-reducing end exosialidases and plays a role in the activation of salmonid fish eggs. This compound is abundant in fetal umbilical cord red blood cells and human malignant ovarian cancer cells.

3-(Acetylthio)propionic acid N-succinimidyl ester is a biochemical reagent used in life sciences research, particularly as a biomaterial or organic compound.

Dansyllysine is utilized to study binding conformations of drugs to human serum albumin and is utilized as a template molecule to form molecularly imprinted monolayers (MIMs) useful to produce optical biosensor recognition elements.

Dansylhydrazide trivaline can exhibit florescence.