dehydroepiandrosterone

Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.

16α-hydroxy Dehydroepiandrosterone (16α-OH-DHEA) is a neurosteroid found in the brain, a precursor to placental estriol biosynthesis.

Dehydroisoandrosterone 3-acetate (Prasterone acetate) is a primary C19 steroid generated by the adrenal cortex.

Prasterone is an endogenous steroid hormone. Prasterone acts as an agonist at ERβ, NMDA, and σ1 receptors, a partial agonist at ERα and AR, and antagonist at GABA-A receptors. It displays a variety of biologocial activities, including enhancing working me

7-keto DHEA Acetate is a natural product applicable for biochemical experiments and drug synthesis studies.

ent-DHEA is the enantiomer of DHEA. DHEA (Prasterone) is one of the most abundant steroid hormones.

Dehydroepiandrosterone-d2 is a deuterated compound of Dehydroepiandrosterone.

Dehydroepiandrosterone sulfate sodium salt (Standard) is a reference standard for research and analysis in studies involving Dehydroepiandrosterone sulfate sodium salt. Dehydroepiandrosterone sulfate sodium salt influences the migration of neurons, arborization of dendrites, and formation of new synapses.

7α-hydroxy Dehydroepiandrosterone (7α-hydroxy DHEA) is an active metabolite of the endogenous steroid hormone dehydroepiandrosterone .17α-hydroxy DHEA is formed from dehydroepiandrosteronevia7-hydroxylation by cytochrome P450s (CYPs).2It increases antigen-induced production of anti-tetanus toxoid and anti-pertussis antigen IgGs in co-cultures of human tonsil-derived B and T cells when used at a concentration of 1 μM.37α-hydroxy DHEA (6.25 mg/kg) increases serum concentrations of anti-lysozyme IgG in mice.1

Dehydroepiandrosterone-2,2,3,4,4,6-d6 is a deuterated compound of Dehydroepiandrosterone. Dehydroepiandrosterone has a CAS number of 53-43-0. Dehydroepiandrosterone (DHEA) is an endogenous steroid hormone that is secreted primarily by the adrenal gland and is the most abundant sex steroid. Although the mechanisms of action of exogenously administered DHEA have not been fully illuminated, they may result in both direct and indirect physiologic effects. Direct effects include GABA-a receptor complex and NMDA receptor modulation and enhanced pancreatic beta cell insulin secretion and anti-glucocorticoid activities.

Dehydroepiandrosterone Sulfate Sodium Salt-d6 is a deuterated compound of Dehydroepiandrosterone Sulfate Sodium Salt. Dehydroepiandrosterone Sulfate Sodium Salt has a CAS number of 1099-87-2.

Dehydroepiandrosterone Glucuronide (Standard) is a reference standard of Dehydroepiandrosterone Glucuronide intended for quantitative analysis, quality control, and related biochemical research applications.

16α-Hydroxydehydroepiandrosterone-d5 (16α-Hydroxy-DHEA-d5) is the deuterated form of 16α-Hydroxydehydroepiandrosterone.

16α-Hydroxydehydroepiandrosterone-[D5] (Standard) is a reference standard of 16α-Hydroxydehydroepiandrosterone-[D5] intended for quantitative analysis, quality control, and related biochemical research applications.

7-Ketodehydroepiandrosterone-[d5] (Standard) is a reference standard of 7-Ketodehydroepiandrosterone-[d5] intended for quantitative analysis, quality control, and related biochemical research applications.

16-Ketodehydroepiandrosterone-[d5] (Standard) is a reference standard of 16-Ketodehydroepiandrosterone-[d5] intended for quantitative analysis, quality control, and related biochemical research applications.

7-Keto DHEA binds to the gamma-aminobutyric acid (GABA) receptor. Studies 7-Keto DHEA reduces ethanol intake in rat models, indicating a modulatory effect on alcohol consumption behavior. 7-Keto DHEA therefore exhibits potential as a investigational compound of alcohol dependence disorders, contributing to the broader field of addiction research.

17a-Hydroxypregnenolone, a pregnane steroid, is a prohormone involved in the synthesis of dehydroepiandrosterone (DHEA).

(S)-(+)-Docosahexaenyl-2'-hydroxy-1'-propylamide (N-Docosahexacnoylethanolamide(22:6)) is a homologue of dehydroepiandrosterone (DHEA). This compound can block Shaker-related voltage-gated potassium channels and inhibits Kv1.2 K+ currents with an IC50 value of 1.5 μM.

Epiandrosterone (EpiA) is a dehydroepiandrosterone metabolite and a precursor of testosterone and estradiol with hypolipidemic and anabolic property.

7β-Hydroxy-epi-androsterone (7β-Hydroxy-EpiA) is an endogenous androgenic derivative of dehydroepiandrosterone that binds to ERβ and exhibits anti-inflammatory and neuroprotective properties [1] [2] [3].

5β-Androstan-3β-ol-17-one (3β-Etiocholanolone; 5β-Epiandrosterone), a 5β-reduced steroid and a significant metabolic derivative of dehydroepiandrosterone (DHEA), demonstrates potent antihyperglycemic actions in C57BL/KsJ genetically diabetic (db/db) mice and possesses a depressive effect on neuronal activity [1] [2].

Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a Ca(2+)-channel blocker that enhances the production of dehydroepiandrosterone sulfate in NCI-H295R human adrenocortical carcinoma cells.

5-Androstenetriol, a steroid and active metabolite of dehydroepiandrosterone (DHEA), demonstrates significant therapeutic effects. Administered at 0.75 mg/25 g body weight, it mitigates radiation-induced mortality and facilitates hematopoietic recovery from surviving stem cells in mice. Moreover, a dosage of 40 mg/kg enhances survival rates in rats subjected to surgical trauma-induced sepsis. Additionally, elevated urinary levels of 5-androstenetriol are observed in women suffering from androgenic alopecia.