cm10

CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.

UCM-1306 is a potent and orally active allosteric modulator (PAM) of the human dopamine D1 receptor. It increases the maximal effect of endogenous dopamine (DA) in both human and mouse D1 receptors. UCM-1306 could improve motor symptoms and address key comorbid cognitive impairment associated with long-term Parkinson's disease (PD).

CM-10-18 is a potent inhibitor of ER α-glucosidase, demonstrating superior in vitro antiviral activity against representative viruses from four viral families causing hemorrhagic fever, and efficiently protecting against the lethality of dengue virus infection in mice.