ciclopirox

Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. Ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, the organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX).

Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.

Ciclopirox olamine (Standard) is the standard substance of Ciclopirox olamine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.

Fosciclopirox disodium suppresses urothelial cancer growth by targeting the γ-secretase complex and selectively delivering the active metabolite, Ciclopirox, throughout the urinary tract. Ciclopirox demonstrates anticancer activity in various solid and hematologic malignancies [1] [2].

Fosciclopirox (CPX-POM), the phosphoryloxymethyl ester of CPX (Ciclopirox Prodrug, CPX-POM), selectively delivers the active metabolite, CPX, to the entire urinary tract following parenteral administration.