chalcone

Chalcone (Cinnamophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.

trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.

Pinocembrin chalcone is an inhibitor of tyrosinase with antimutagenic effects. Pinocembrin chalcone can be used in studies about the prevention of gastric ulcers.

Pinostrobin chalcone, a chalcone analog isolated from the leguminous plant, Mucuna pruriens, exhibits anticancer activity with an IC50 value of 20.42±2.23 μg/mL against MDA-MB-231 and 22.51±0.42 μg/mL against the HT-29 colon cancer cell line.

Eriodictyol chalcone is a natural product exhibiting inhibitory activity against 17β-HSD, suitable for biochemical experiments and drug synthesis research.

NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. 3. Flavokawain A (Flavokavain A) may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-κB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages.

Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.

(E)-Cardamonin (Alpinetin chalcone) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera. It is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM. It has received growing attention from the scientific community due to the expectations toward its benefits to human health.

Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator. It sensitizes HeLa cells to Cisplatin by targeting FoxO3a via the AKT and ERK/p38 MAPK pathways.

Cardamonin (Cardamomin) is a chalcone isolated from Alpiniae katsumadai. It has anticancer, anti-inflammatory, antimicrobial, antioxidant and anti-diabetic activities. It can inhibit mTOR, NF-κB, Akt, STAT3, Wnt/β-catenin and COX-2, inhibit the growth of breast cancer, and can be used to study acute kidney injury and chronic renal fibrosis.

Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.

(E)-Pinocembrin chalcone is an antibacterial compound that can be derived from Helichrysum trilineatum.

4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity

2,2'-Dihydroxy chalcone is a potent inhibitor of β-glucuronidase (IC50=1.6±0.2 μM) and lysozyme (IC50=1.4±0.2 μM) release from rat neutrophils stimulated with fMLP/CB.2,2'-Dihydroxy chalcone has inhibitory activity against Escherichia coli, Shigella fowleri, Staphylococcus albicans and Staphylococcus aureus.

2-Hydroxy-3-methoxy chalcone has anticancer activity and inhibits colon cancer.

Naringenin chalcone is a natural product isolated from the stem of the plant Machaerium isadelphum (Fabaceae).Naringenin chalcone has anti-inflammatory activity.

Pinostrobin chalcone (Standard) is a reference standard for research and analysis in studies involving Pinostrobin chalcone. Pinostrobin chalcone, a chalcone analog isolated from the leguminous plant, Mucuna pruriens, exhibits anticancer activity with an IC50 value of 20.42±2.23 μg/mL against MDA-MB-231 and 22.51±0.42 μg/mL against the HT-29 colon cancer cell line.

Naringenin chalcone (Standard) is a reference standard for research and analysis in studies involving Naringenin chalcone. Naringenin chalcone is a natural product isolated from the stem of the plant Machaerium isadelphum (Fabaceae).Naringenin chalcone has anti-inflammatory activity.

Homoeriodictyol chalcone（2',4,4',6'-tetrahydroxy-3-methoxychalcone） is a natural chalcone glucoside used in biochemical experiments and organic synthesis.

Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.

Neohesperidin Dihydrochalcone (Neohesperidin DC) is an artificial sweetener derived from citrus.

4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.

4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.

4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.