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By Target- Calcium Channel
- Complement System(1)
- P2Y Receptor(1)
- p38 MAPK(1)
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Results for "
c3a receptor agonist
" in TargetMol Product Catalog- Inhibitors & Agonists2
C3a Receptor Agonist
Complement 3a Receptor Agonist, C3a receptor agonist 1
T38287944997-60-8
C3a Receptor Agonist (C3a receptor agonist 1) binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from being mobilized in a model of intestinal ischemia-reperfusion injury. C3aRs are expressed on neural progenitor cells and immature neurons in adult mice. C3a stimulates differentiation of neural progenitor cells in vitro.
- $89
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MRS2690 disodium
T212457
MRS2690 disodium is a selective agonist of the P2Y14 receptor. It inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and causing concentration-dependent vasoconstriction in porcine coronary arteries. MRS2690 disodium induces intracellular calcium mobilization, activates P38, and stimulates [35S]GTPγS binding on the membrane of RBL-2H3 cells. It also enhances the β-hexosaminidase (β-Hex) release induced by antigen (NP-BSA) and C3a. This compound is useful for research in ischemic heart disease.
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