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By Target- Histone Methyltransferase
- Sirtuin(1)
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Results for "
bml-278
" in TargetMol Product Catalog- Inhibitors & Agonists1
BML-278
BML278, BML 278
T77697120533-76-8
BML-278 is a SIRT1 activator with an EC150 of 1 μM. It increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, improving early embryonic development. BML-278 induces cell cycle arrest at the G1 S phase in primary human mesenchymal stromal cells, delaying senescence. It also reduces microtubule protein acetylation in U937 cells and increases mitochondrial density in mouse C2C12 myoblasts.
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