beta-carboline

Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family.

1-Ethoxycarbonyl-β-carboline is an anti-inflammatory compound that inhibits superoxide anion production (IC₅₀ = 4.87 μg/mL) and elastase release (IC₅₀ = 6.29 μg/mL).

β-Carboline-1-carboxylic acid is an alkaloid that has been found in P. quassioides and has diverse biological activities. It reduces LPS-induced increases in MCP-1, TNF-α, IL-6, and IL-1β levels in RAW 264.7 cells when used at a concentration of 15 µg/ml and inhibits the epithelial-to-mesenchymal transition (EMT) induced by TGF-β1 in A549 cells. β-Carboline-1-carboxylic acid induces cytotoxicity in CT26.WT, K562, and SGC-7901 cells (IC50s = 14.96, 22.11, and 19.7 µg/ml, respectively) but not HepG2 or A549 cells (IC50s = 36.41 and 41.51 µg/ml, respectively). It also inhibits cAMP phosphodiesterase with an IC50 value of 96 µM.

7-Fluoro-2,3,4,9-tetrahydro-1H-beta-carboline, with CAS No. 177858-80-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Fluoro-2,3,4,9-tetrahydro-1H-beta-carboline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Ethyl beta-carboline-1-propionate is a useful organic compound for research related to life sciences and the catalog number is T123952.

4-Hydroxy-1-methoxycarbonyl-beta-carboline is a useful organic compound for research related to life sciences and the catalog number is T124278.

1-Methoxymethyl-beta-carboline is a useful organic compound for research related to life sciences and the catalog number is T124657.

7-Hydroxy-beta-carboline-1-propionic acid is a useful organic compound for research related to life sciences and the catalog number is T125336.

7-Methoxy-beta-carboline-1-propionic acid is a useful organic compound for research related to life sciences and the catalog number is T125967.

1-Hydroxymethyl-beta-carboline glucoside is a natural product from Picrasmae Ramulus et Folium.

1-vinyl-4-dimethoxy-beta-carboline is a natural product from Picrasma javanica.

1-Methoxycarbonyl-beta-carboline-N-oxide is a natural product for research related to life sciences. The catalog number is TN6652 and the CAS number is 74690-74-7.

1-Methoxycarbonyl-β-carboline (1-Methoxycarbonyl-beta-carboline) is an alkaloid from Ailanthus altissima.

β-Carboline-1-propionic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

1-Acetyl-β-carboline is a bioactive metabolite derived from Streptomyces kasugaensis that exhibits antibacterial properties, enhances tyrosinase activity, reduces ERK phosphorylation, and increases melanin production, while demonstrating antibacterial efficacy against methicillin-resistant Staphylococcus aureus strains with minimum inhibitory concentrations ranging from 128 to 256 μg/mL, supporting the use of 1-Acetyl-β-carboline in the investigation in antimicrobial and pigmentation-related biochemical research.

Crenatine possesses antibacterial activity, it is more effective against Gram-positive than Gram-negative bacteria.

1-Formyl-β-carboline is an alkaloid derived from the leaves of Ailanthus altissima.

Harmane (Loturine) is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee and tobacco smoke.

Flavopereirine is a beta-carboline alkaloid.

Lon 954, also known as Harmine, is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds.

Manzamine A hydrochloride is an orally active beta-carboline alkaloid that exhibits specific inhibitory effects on GSK-3β (IC50 = 10.2 μM) and CDK-5 (IC50 = 1.5 μM). Additionally, it targets vacuolar ATPases, leading to the inhibition of autophagy in pancreatic cancer cells. Manzamine A hydrochloride possesses antimalarial and anticancer properties, and also demonstrates potent activity against HSV-1[4].

Harmalol (Harmidol) is a bioactive beta-carboline and a member of the harmala alkaloids

4-Methoxy-1-methoxycarbonyl-β-carboline is a natural product for research related to life sciences. The catalog number is TN6008 and the CAS number is 60807-25-2.

1-(3,4,5-Trihydroxypentanoyl)-β-carboline is a natural product for research related to life sciences. The catalog number is TN6093 and the CAS number is 180995-40-8.