atorvastatin

Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an HMG-CoA reductase inhibitor with oral activity. Atorvastatin hemicalcium salt is used to lower cholesterol.

Atorvastatin, an orally active HMG-CoA reductase inhibitor, effectively lowers blood lipids by activating liver cytochrome p450 to accelerate metabolism. Atorvastatin inhibits the proliferation and invasion of human SV-SMC cells with IC50 values of 0.39 μM and 2.39 μM, respectively. [Atorvastatin] combined with clopidogrel may lead to increased thrombotic events in patients.

Atorvastatin Hemicalcium Trihydrate, an orally active HMG-CoA reductase inhibitor, effectively reduces blood lipids. It also inhibits human SV-SMC proliferation and invasion, showing IC50 values of 0.39 μM and 2.39 μM, respectively.

2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of atorvastatin calcium salt, a potent HMG-CoA reductase inhibitor (IC50 = 8 nM).

Atorvastatin Sodium (Lipitor) is a competitive inhibitor of HMG-CoA reductase and increases the expression of low density lipoprotein (LDL) receptors on hepatocytes. Atorvastatin Sodium treatment inhibits aquaporin 4 to reduce ischaemic brain oedema.

2-Hydroxy atorvastatin lactone, a metabolite of Atorvastatin, is an orally active HMG-CoA reductase inhibitor that efficiently reduces blood lipids [1][2].

O-Methyl Atorvastatin is an impurity of Atorvastatin that is an orally active inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, has the ability to effectively decrease blood lipids.

3-Oxo Atorvastatin, an impurity of Atorvastatin, acts as an HMG-CoA reductase inhibitor and effectively decreases blood lipids.

Atorvastatin acetonide [Atorvastatin Impurity B] is an impurity of Atorvastatin, an HMG-CoA reductase inhibitor known for its efficacy in lowering blood lipids.

Atorvastatin Epoxy Tetrahydrofuran Impurity is an isolated oxidative degradation product of Atorvastatin, an orally active HMG-CoA reductase inhibitor.

ortho-Hydroxy Atorvastatin-d5 Calcium Salt is a deuterated compound of ortho-Hydroxy Atorvastatin Calcium Salt. ortho-Hydroxy Atorvastatin Calcium Salt has a CAS number of 265989-47-7.

Desfluoro-atorvastatin is an Atorvastatin impurity. Atorvastatin is an orally active inhibitor of HMG-CoA reductase. It has the ability to effectively decrease blood lipids.

Atorvastatin acetonide tert-butyl ester, a valuable pharmaceutical intermediate, is used in preparing Atorvastatin salts, an HMG-CoA reductase inhibitor.

Atorvastatin strontium is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia.

Difluoro atorvastatin is an Atorvastatin impurity. Atorvastatin is an orally active HMG-CoA reductase inhibitor and it has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion (IC50s: 0.39 μM and

para-Hydroxy Atorvastatin-d5 Calcium Salt is a deuterated compound of para-Hydroxy Atorvastatin Calcium Salt. para-Hydroxy Atorvastatin Calcium Salt has a CAS number of 214217-88-6.

Atorvastatin magnesium trihydrate is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia.

Atorvastatin, (3S,5R)- is an Atorvastatin impurity.

Atorvastatin ethyl ester, a derivative of Atorvastatin, exhibits potent inhibition of 9-cis-RA-induced Gal4 reporter activity.

ortho-Hydroxy Atorvastatin-d5 Lactone is a deuterated compound of ortho-Hydroxy Atorvastatin Lactone.

ent-Atorvastatin is a selective and competitive inhibitor of HMGCR (HMG-CoA reductase).

Atorvastatin magnesium is an HMG-CoA inhibitor.

4-hydroxy Atorvastatin is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin.

Atorvastatin methyl ester is a derivative of Atorvastatin. It inhibits the 9-cis-RA-induced Gal4 reporter activity more strongly than Atorvastatin.