20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3866 | Macelignan | Anwuligan,(+)-Anwulignan | Others , COX |
Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. | |||
T2210 | Genipin | (+)-Genipin | Others , Autophagy |
Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis. | |||
TN1788 | Isookanin | Amylase | |
Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml). | |||
T0247 | Acarbose | BAY g 5421 | Glucosidase |
Acarbose (BAY g 5421) is an inhibitor of α-Glucosidases with antihyperglycemic activity. | |||
T21694 | (R)-Lisofylline | (R)-Lisophylline | STAT |
(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM). (R)-Lisofylline interrupts IL-12 signaling-mediated STAT4 activation and can be used in studies about the treat... | |||
T4328 | OSS_128167 | SIRT6-IN-1 | HBV , Sirtuin |
OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 μM), SIRT1(IC50=1578 μM) and SIRT2(IC50=751 μM). | |||
T3675 | 1-Deoxynojirimycin | Duvoglustat,Moranoline,moranolin | PI3K , Glucosidase |
1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus. | |||
T0314 | Hexylresorcinol | 4-Hexylresorcinol | Apoptosis , Tyrosinase , Antibacterial , Parasite |
Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections. | |||
T6587 | Mitiglinide Calcium | KAD-1229,S21403 | ATPase , Potassium Channel |
Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells. | |||
T1824 | TGR5 Receptor Agonist | GPCR19 | |
TGR5 is a potent TGR5(GPCR19) agonist. | |||
T21344 | 1-Deoxynojirimycin hydrochloride | Moranoline,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin | PI3K , Antibacterial , Antibiotic , Glucosidase |
1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia. | |||
T1530 | Mitiglinide calcium hydrate | KAD-1229 calcium hydrate,Mitiglinide calcium,S-21403 calcium hydrate | Potassium Channel |
Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic ... | |||
T83646 | (S)-OSMI 3 | Ent-OSMI-3 | Others |
(S)-OSMI 3 (Ent-OSMI-3) has anti-inflammatory and anti-tumour activity and can be used to study diabetes and neurodegenerative diseases. | |||
T26982 | Cerebrocrast | IOS 11212,IOS-11212,IOS11212 | Others |
Cerebrocrast (IOS-11212) is an anti-inflammatory and hypoglycemic activity that promotes H+ and Cl- cotransport in rat liver mitochondria, blocks human platelet activation, and can be used to study diabetes. | |||
TN1132 | Procyanidin A2 | IL Receptor , TNF , transporter , Antibacterial | |
Procyanidin A2 is a potential precursor of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone, exhibits antioxidant, anti-inflammary, anti-hyperglycemia, and anti-type 2 diabetes activities. Procyanidin A2 demonstrates liver cell... | |||
T27841 | Lobeglitazone Sulfate | CKD501 Sulfate,CKD501,CKD-501 Sulfate,CKD 501 Sulfate,CKD 501,CKD-501,Lobeglitazone Sulfate. trade name Duvie, Chong Kun Dang | NOD |
Lobeglitazone Sulfate(CKD-501 Sulfate) is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and hepatic inflammation, and can be used in the study of type 2... | |||
T3851 | Vicenin 2 | Vicenin -2 | RAAS |
Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective,... | |||
T3403 | Glabridin | Q-100692,KB-289522,LS-176045 | Reactive Oxygen Species , Tyrosinase , GABA Receptor , Antibacterial , PPAR |
Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on... | |||
T3394 | Timosaponin BII | Prototimosaponin A III | Beta Amyloid , Others , BACE |
Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the... | |||
T11016 | DGAT-1 inhibitor 2 | Transferase | |
DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor; anti-obesity drug. Objective: DGAT-1 acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) is one of two known DGAT enzymes that catalyze the final step of triglyceride s... |