anaphase-promoting

TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.

Apcin-A is an anaphase-promoting complex (APC) inhibitor. It interacts strongly with Cdc20 and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V.

CFM-1 is an antagonist of the anaphase-promoting complex (APC)-2. It also is a cell cycle and apoptosis regulatory protein (CARP)-1 interaction antagonist.

Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V.

TAME (Tosyl-Arginine Methyl Este), an inhibitor of the late-promoting complex (APC C or APC), inhibits APC-dependent protein hydrolysis by competing for APC binding with the C-terminal isoleucine-arginine tail of the APC activator cytokinesis cycle 20 (Cdc20). TAME binds to and prevents APC binding by Cdc20 and Cdh20. TAME binds to APC and prevents its activation by Cdc20 and Cdh1.

Apcin is a potent and competitive inhibitor of anaphase-promoting complex cyclosome (APC C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. It acts by blockin