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ampa receptor desensitization

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    3
    TargetMol | All_Pathways
Cyclothiazide
T45732259-96-3
Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptorsthat potently inhibits AMPA receptor desensitization, positively modulating its response to glutamic acid (EC50 = 3.8 M).
  • $48
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JAMI1001A
T383921001019-46-0
JAMI1001A is a positive allosteric modulator of the AMPA receptor, effectively modulating the deactivation and desensitization of both [flip] and [flop] receptor isoforms.
  • $970
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AMPA receptor modulator-6
T79504516491-33-1
AMPA receptor modulator-6 (Compound 6) is a unique dimeric positive allosteric modulator that effectively stabilizes the dimer interface of AMPA receptors by physically bridging two adjacent ligand-binding domains. This structural anchoring significantly slows receptor desensitization and deactivation, thereby enhancing glutamate-mediated synaptic transmission.
  • $195
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