acetylcholine chloride

Acetylcholine Chloride is the chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride (Pilofrin) mimics the parasympathomimetic effect of the endogenous compound acetylcholine. Administered as an ophthalmic solution, this drug stimulates the cholinoceptors in the sphincter muscle of the iris, causing the pupil to constrict.

Carbachol (Carbamoylcholine chloride), an analog of acetylcholine, serves as a valuable tool in the investigation of various physiological responses mediated by nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. These responses include smooth muscle contraction, gut motility, and neuronal signaling. Known for its agonistic properties, Carbachol activates both nAChR and mAChR, with reported Ki values ranging from 10 to 10,000 nM for different receptor types and experimental preparations.

Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.

Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.

Trospium chloride (Spasmex) is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. Trospium chloride has not been implicated in causing liver enzyme elevations or clinically apparent acute liver injury.

Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma.

Bethanechol chloride (Carbamyl-β-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. It is used to increase smooth muscle tone in the GI tract following abdominal surgery or to treat urinary retention without obstruction. Possible side effects include hypotension, heart rate changes, and bronchial spasm.

Choline-d9 chloride is a deuterium-labelled derivative of choline chloride for isotope tracing. Choline chloride, an essential nutrient, activates α7 nicotinic acetylcholine receptors and exhibits anti-inflammatory and analgesic properties.

Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emergency surgical procedures of short to intermediate duration and during intubation of the trachea.

Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.

Edrophonium chloride is an acetylcholinesterase (AChE) inhibitor that is known to prevent the breakdown of the neurotransmitter acetylcholine by binding specifically to its catalytic site.

(±)-Muscarine chloride is the racemate of Muscarine chloride, a prototypical agonist for the muscarinic acetylcholine receptor [1] [2].

Homidium Chloride is the chloride salt of ethidium (a fluorochrome), Ethidium Chloride intercalates within double-stranded nucleic acids, particularly DNA. In molecular biology, the bromide salt of ethidium is used to detect and visualize DNA after electrophoresis or in cytochemical preparations. In veterinary pharmacology, it is used as a trypanosomicide. Ethidium bromide and chloride are toxic substances and potent noncompetitive antagonists of the nicotinic acetylcholine receptor.

Ambenonium chloride tetrahydrate is a salt of ambenonium --- a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia gravis occurs when the body produces antibodies against acetylcholine receptors, and thus inhibits signal transmission across the myoneural junction. Ambenonium chloride is a rapid indirect-acting cholinergic agonist that reversibly blocks the activity of acetylcholinesterase, thereby prevents acetylcholine hydrolysis and prolonging its activity on nicotinic receptors at the neuromuscular junction.

Pipoxolan (free base) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and inhibited the decrease in blood pressure caused by stimulation of the vagus nerve. The drug is marketed under tradename Rowapraxin worldwide for the treatment of spasms and colics in the gastrointestinal tract, gallbladder and urogenital area, bronchial spasms, spastic menstrual cramps. Recent studies have shown that pipoxalan has anticancer activity and inhibits proliferation of leukemia cells in animal models.

Pipoxolan (HCl) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and inhibited the decrease in blood pressure caused by stimulation of the vagus nerve. The drug is marketed under tradename Rowapraxin worldwide for the treatment of spasms and colics in the gastrointestinal tract, gallbladder and urogenital area, bronchial spasms, spastic menstrual cramps. Recent studies have shown that pipoxalan has anticancer activity and inhibits proliferation of leukemia cells in animal models.

Esoxybutynin Chloride is (S)-enantiomer of oxybutynin. Esoxybutynin Chloride exerts antimuscarinic properties. Racemic oxybutynin is used clinically to treat urinary incontinence. Sepracor was developing (S)-oxybutynin, a single-isomer version of Alza's Ditropan (racemic oxybutynin), a muscarinic acetylcholine receptor antagonist, as a potential treatment for urinary incontinence.

Acetylcholine-d9 (chloride) is the deuterated form of Acetylcholine chloride. Acetylcholine chloride (ACh chloride) serves as a neurotransmitter and functions as a potent cholinergic agonist. It modulates dopaminergic (DAergic) neuronal activity by stimulating nicotinic acetylcholine receptors (nAChRs) and inhibits the aggregation of p53 mutant peptides in vitro.

Acetylcholine-d4(chloride) is the deuterated form of Acetylcholine chloride. Acetylcholine chloride (ACh chloride) functions as a neurotransmitter and is a potent cholinergic agonist. It modulates dopaminergic (DAergic) neuron activity by stimulating nicotinic acetylcholine receptors (nAChRs). Additionally, Acetylcholine chloride inhibits the aggregation of p53 mutant peptides in vitro.

Choline chloride (Standard) is a reference standard for research and analysis in studies involving Choline chloride. Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

Choline-D9 Chloride (Standard) is a reference standard of Choline-D9 Chloride intended for quantitative analysis, quality control, and related biochemical research applications. Choline-d9 chloride is a deuterium-labelled derivative of choline chloride for isotope tracing. Choline chloride, an essential nutrient, activates α7 nicotinic acetylcholine receptors and exhibits anti-inflammatory and analgesic properties.

Acetylcholine-D4 Chloride (Standard) is a reference standard of Acetylcholine-D4 Chloride intended for quantitative analysis, quality control, and related biochemical research applications. Acetylcholine-d4(chloride) is the deuterated form of Acetylcholine chloride. Acetylcholine chloride (ACh chloride) functions as a neurotransmitter and is a potent cholinergic agonist. It modulates dopaminergic (DAergic) neuron activity by stimulating nicotinic acetylcholine receptors (nAChRs). Additionally, Acetylcholine chloride inhibits the aggregation of p53 mutant peptides in vitro.

Acetylcholine-D9 Chloride (Standard) is a reference standard of Acetylcholine-D9 Chloride intended for quantitative analysis, quality control, and related biochemical research applications. Acetylcholine-d9 (chloride) is the deuterated form of Acetylcholine chloride. Acetylcholine chloride (ACh chloride) serves as a neurotransmitter and functions as a potent cholinergic agonist. It modulates dopaminergic (DAergic) neuronal activity by stimulating nicotinic acetylcholine receptors (nAChRs) and inhibits the aggregation of p53 mutant peptides in vitro.