T2908

Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms. Palmitic acid has antitumor activity.

V-11-0711 is an inhibitor of Chk-α, which may be essential in cancer cell proliferation.

VA-K-14 hydrochloride(VAK14 HCl) is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.

V-11-0711 HCl is a selective and highly effective choline kinase α (ChoKα) inhibitor that inhibits the catalytic activity of Chk.

UTA1inh-C1 is a novel inhibitor of kidney urea transporter UT-A1.

V-116517, a TRPV1 antagonist, is used potentially for the treatment of severe pain due to osteoarthritis and chronic pain due postherpetic neuralgia (PHN).

VA5 is an transamidase inhibitor by direct binding at the transamidase site. VA5 also inhibits GTP-binding activities. It interaction at the transamidase site locks the protein in the extended/open conformation to disorganize/inactivate the GTP binding/GT

Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.

Palmitic acid-1-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid (T2908) is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid (T2908) is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6

Palmitic acid-1,2,3,4-13C4 is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid (T2908) is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellular proteins, promotes protein-vesicle interactions, and regulates various G protein-coupled receptor functions.1Red blood cell palmitic acid levels are increased in patients with metabolic syndrome compared to patients without metabolic syndrome and are also increased in the plasma of patients with type 2 diabetes compared to individuals without diabetes.3,4

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid (T2908) is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic acid (T2908) is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.3,4,5,6,7

Palmitic acid-13C2 is the 13C-labeled Palmitic acid. Palmitic acid (T2908) is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid (T2908) can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.

Palmitic acid-16,16,16-D3 is a deuterated compound of Palmitic acid. Palmitic acid (T2908) has a CAS number of 57-10-3. Palmitic acid (T2908) is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.

Palmitic acid-D2 is the deuterated form of Palmitic acid. Palmitic acid (T2908) is a long-chain saturated fatty acid commonly found in animals and plants. It is known to induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in mouse granulosa cells.

Palmitic acid-D9 is the deuterated form of Palmitic acid. A long-chain saturated fatty acid, Palmitic acid (T2908) is commonly found in animals and plants. It has the ability to induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in murine granulosa cells.

Palmitic acid-D4-1 is the deuterated form of Palmitic acid. This compound is a long-chain saturated fatty acid commonly found in animals and plants. Palmitic acid (T2908) has the ability to induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in murine granulosa cells.

Palmitic acid-D31 is the deuterated form of palmitic acid. Palmitic acid (T2908) is a long-chain saturated fatty acid commonly found in animals and plants. It can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in murine granulosa cells.

Palmitic acid-13C16 is a form of Palmitic acid (T2908) that is labeled with 13C. As a long-chain saturated fatty acid, Palmitic acid (T2908) is commonly found in both animals and plants. It can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in mouse granulosa cells.

Palmitic acid-D17 is the deuterated form of Palmitic acid. Palmitic acid (T2908) is a long-chain saturated fatty acid commonly found in both animals and plants. It has the ability to induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in mouse granulosa cells.

Palmitic acid-D4 is the deuterated form of Palmitic acid. This compound is a long-chain saturated fatty acid commonly found in animals and plants. Palmitic acid (T2908) is known to induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in murine granulosa cells.

Palmitic acid-D1 is the deuterated form of Palmitic acid. Palmitic acid (T2908) is a long-chain saturated fatty acid commonly found in animals and plants. It can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in murine granulosa cells.

Palmitic acid-15,15,16,16,16-D5 is a deuterated form of Palmitic acid. This compound is a long-chain saturated fatty acid commonly found in animals and plants. Palmitic acid (T2908) can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in mouse granulosa cells.