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Search Results for " nsclc "

Targets

124

Compounds

10

Natural Products

29

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T9460 IMDK PI3K
iMDK quarterhydrate is a potent PI3K inhibitor that inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate synergistically inhibits non-small cell lung cancer (NSCLC) with MEK inhibitors withou...
T6455 CP-91149 Phosphorylase
CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.
T40254 MRTX-1719 Histone Methyltransferase
MRTX-1719 is a potent, first-in-class, selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells.
T9929 Ramucirumab VEGFR
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
T10777 CG347B HDAC
CG347B is a selective inhibitor of HDAC6.
T8732 CTPI-2 Others , Mitochondrial Metabolism
CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 ha...
T6734 WZ8040 EGFR
WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).
T11224 Rineterkib ERK-IN-1 ERK , Raf
Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.
T12695 RBN-2397 PARP
RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM.
T13176 TNO155 Batoprotafib Phosphatase
TNO155 is a protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11) inhibitor(IC50 : 0.011 µM),with potential antineoplastic activity.
T8684 Sotorasib AMG-510 Ras
Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib ...
T5414 Glumetinib SCC244 c-Met/HGFR
Glumetinib (SCC244) (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM).
T22318 Taletrectinib DS-6051b,AB-106 Trk receptor , ROS , ROS Kinase
Taletrectinib (AB-106) is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively.
T8151 Mobocertinib tak788 EGFR
Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent
T22254 Alflutinib AST2818,ASK120067 EGFR , P450
Alflutinib (ASK120067) is an inhibitor of EGFR, and its targets including EGFR activating mutations and T790M, thus leading to tumor growth inhibition.
T39275 Befotertinib D-0316,Befotertinib EGFR
Befotertinib (D-0316) is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cell lung cancer.
T8327 ONO-7475 Trk receptor , TAM Receptor
ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase
T16996 TAS6417 Apoptosis , EGFR
TAS6417 is an EGFR inhibitor and is an efficacious drug candidate for patients with NSCLC (IC50: ranging from 1.1-8.0 nM).
T16545 Pivanex Pivalyloxymethyl butyrate,AN-9 Apoptosis , HDAC , Bcr-Abl
Pivanex (Pivalyloxymethyl butyrate) is an orally active HDAC inhibitor and an antimetastatic and antiangiogenic agent. Pivanex downregulates the Bcr-Abl protein and enhances apoptosis.
TQ0255 Olafertinib CK-101,EGFR-IN-3,RX-518 EGFR
Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.
T5462 Almonertinib HS-10296 EGFR
Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.
T7175 Alflutinib mesylate AST2818 mesylate EGFR
Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.
T15735 Leptomycin B CI 940,LMB CRM1 , Antibiotic , Antifungal
Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a ...
T5675 Almonertinib hydrochloride HS-10296 hydrochloride EGFR
Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.
T22443 Triglycidyl isocyanurate Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI Apoptosis
Triglycidyl isocyanurate (Teroxirone) is a triazene triepoxide with antineoplastic and antiangiogenic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl isocyanurate alk...
T20168 Aurothiomalate sodium Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate Others , PKC
Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate ...
T3061 Lorlatinib PF-6463922,PF-06463922,Loratinib Apoptosis , Tyrosine Kinases , ROS , ALK , ROS Kinase
Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity.
T8656 CAY10404 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T Apoptosis , Akt , COX
CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cel...
T6823 E3330 HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
T21312 Afatinib Afatinib free base,BIBW 2992 EGFR , Autophagy
Afatinib (BIBW 2992) is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively).
T16492 PF-06459988 EGFR
PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) mutant inhibitor. PF-06459988 has high efficiency and high affinity for EGFRs double mutants containin...
T1773 Afatinib Dimaleate BIBW2992,Afatinib,BIBW 2992MA2,Afatinib (BIBW2992) Dimaleate EGFR , HER , Autophagy
Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic act...
T6804 Chetomin Chaetomin,NSC289491,BRN0077366 Apoptosis , HSP , HIF
Chetomin (BRN0077366) is an inhibitor of HIF-1 by weaken transcription of HIF-1, disrupting the binding of HIF-1α and HIF-2α to p300 at low nanomolar concentrations.
T3181 SW044248 Topoisomerase
SW044248 is a noncanonical Top1 inhibitor. It has selective toxicity for NSCLC cells.
T36404L PRLX-93936 HCL PRLX-93936 hcl(903499-49-0 Free base) Ferroptosis , Reactive Oxygen Species
PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.
T9601 Tepotinib hydrochloride(1 : x) c-Met/HGFR , P-gp , ABC
Tepotinib hydrochloride(1 : x) is an orally bioavailable, mesenchymal-epithelial transition (MET) TKI developed mainly for selected NSCLC patients with METex14 skipping mutations.
T72043 SCFSkp2-IN-2 Apoptosis , E1/E2/E3 Enzyme
SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM. It demonstrates antitumor activities by inducing apoptosis in non-small cell lung cancer (NSCLC) cells.
T6269 Bemcentinib R428,BGB324 TAM Receptor
Bemcentinib (R428) is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC.
T9901A-002 Enoblituzumab MGA271,TJ-271 Others
Enoblituzumab is a humanized IgG1 κmab monoclonal antibody that recognizes human B7-H3 protein and can be used to study solid tumors such as non-small cell lung cancer (NSCLC).
T11162 EGFR-IN-8 EGFR , c-Met/HGFR
EGFR-IN-8, a dual inhibitor targeting both EGFR and c-Met, shows potential as a promising candidate for further development in treating EGFR TKI-resistant NSCLC.
T35901 EGFR-IN-99 JBJ-03-142-02 EGFR , HER
EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor with antiproliferative activity for the study of non-small cell lung cancer (NSCLC).
T61016 EMI1 EGFR
EMI1 can be used in the mutant EGFR-associated, drug-resistant non-small-cell lung cancer(NSCLC) research. EMI1 is an inhibitor of EGFR L858R/T790M/C797S and EGFR ex19del/T790M/C797S [1].
T9754 BLU-945 BLU945,BLU 945 EGFR
BLU-945 is a potent, highly selective, reversible, and orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, effective against EGFR with L858R and/or exon 19 deletion mutations, T790M, and C797...
T35391 Vibostolimab (anti-TIGIT) Vibostolimab (anti-TIGIT) Others
Vibostolimab is a monoclonal antibody against T cell immune proteins and the ITIM domain.Vibostolimab has shown anti-tumor activity in in vitro trials and can be used to study non-small cell lung cancer (NSCLC) and melan...
T67934 MRT-2359 Others
MRT-2359 is a potent and orally available GSPT1 reducer with antitumour activity.MRT-2359 inhibits the growth of drug-resistant non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) cells.MRT-2359 exhibits...
T76873 Nidanilimab CAN04 IL Receptor
Nidanilimab (CAN04) is a fully humanized IL1RAP monoclonal antibody with a Kd value of 1.10 pM. Nidanilimab has antitumor activity, cutting off the IL1α and IL1β signaling pathways and inducing the immune system to destr...
T6092 Sapitinib AZD-8931 EGFR
Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib or Lapatinib against NSCLC cell, 100-fold more specific for the E...
T4605 NT157 IGF-1R , STAT
NT157 is a small molecule tyrphostin targeting IRS protein and has the potential to inhibit IGF-1R and STAT3 signaling pathways in TME cancer cells and stromal cells, resulting in decreased cancer cell survival.
T10745 CDK9-IN-7 CDK
CDK9-IN-7 is a highly selective and orally active CDK9/cyclin T inhibitor (IC50: 11 nM), which exhibits more potent over other CDKs (CDK4/cyclinD: 148 nM; CDK6/cyclinD: 145 nM).
T60446 LCS3 Apoptosis , Glutathione reductase
LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 μM and 3.8 μM, respectively. LCS3 has antitumour activity, in...

Compounds

iMDK
T9460
Synonym:
Target: PI3K
CP-91149
T6455
Synonym:
Target: Phosphorylase
MRTX-1719
T40254
Synonym:
Target: Histone Methyltransferase
Ramucirumab
T9929
Synonym:
Target: VEGFR
CG347B
T10777
Synonym:
Target: HDAC
CTPI-2
T8732
Synonym:
Target: Others, Mitochondrial Metabolism
WZ8040
T6734
Synonym:
Target: EGFR
Rineterkib
T11224
Synonym: ERK-IN-1
Target: ERK, Raf
RBN-2397
T12695
Synonym:
Target: PARP
TNO155
T13176
Synonym: Batoprotafib
Target: Phosphatase
Sotorasib
T8684
Synonym: AMG-510
Target: Ras
Glumetinib
T5414
Synonym: SCC244
Target: c-Met/HGFR
Taletrectinib
T22318
Synonym: DS-6051b,AB-106
Target: Trk receptor, ROS, ROS Kinase
Mobocertinib
T8151
Synonym: tak788
Target: EGFR
Alflutinib
T22254
Synonym: AST2818,ASK120067
Target: EGFR, P450
Befotertinib
T39275
Synonym: D-0316,Befotertinib
Target: EGFR
ONO-7475
T8327
Synonym:
Target: Trk receptor, TAM Receptor
TAS6417
T16996
Synonym:
Target: Apoptosis, EGFR
Pivanex
T16545
Synonym: Pivalyloxymethyl butyrate,AN-9
Target: Apoptosis, HDAC, Bcr-Abl
Olafertinib
TQ0255
Synonym: CK-101,EGFR-IN-3,RX-518
Target: EGFR
Almonertinib
T5462
Synonym: HS-10296
Target: EGFR
Alflutinib mesylate
T7175
Synonym: AST2818 mesylate
Target: EGFR
Leptomycin B
T15735
Synonym: CI 940,LMB
Target: CRM1, Antibiotic, Antifungal
Almonertinib hydrochloride
T5675
Synonym: HS-10296 hydrochloride
Target: EGFR
Triglycidyl isocyanurate
T22443
Synonym: Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI
Target: Apoptosis
Aurothiomalate sodium
T20168
Synonym: Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate
Target: Others, PKC
Lorlatinib
T3061
Synonym: PF-6463922,PF-06463922,Loratinib
Target: Apoptosis, Tyrosine Kinases, ROS, ALK, ROS Kinase
CAY10404
T8656
Synonym: 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T
Target: Apoptosis, Akt, COX
E3330
T6823
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, DNA/RNA Synthesis
Afatinib
T21312
Synonym: Afatinib free base,BIBW 2992
Target: EGFR, Autophagy
PF-06459988
T16492
Synonym:
Target: EGFR
Afatinib Dimaleate
T1773
Synonym: BIBW2992,Afatinib,BIBW 2992MA2,Afatinib (BIBW2992) Dimaleate
Target: EGFR, HER, Autophagy
Chetomin
T6804
Synonym: Chaetomin,NSC289491,BRN0077366
Target: Apoptosis, HSP, HIF
SW044248
T3181
Synonym:
Target: Topoisomerase
PRLX-93936 HCL
T36404L
Synonym: PRLX-93936 hcl(903499-49-0 Free base)
Target: Ferroptosis, Reactive Oxygen Species
Tepotinib hydrochloride(1 : x)
T9601
Synonym:
Target: c-Met/HGFR, P-gp, ABC
SCFSkp2-IN-2
T72043
Synonym:
Target: Apoptosis, E1/E2/E3 Enzyme
Bemcentinib
T6269
Synonym: R428,BGB324
Target: TAM Receptor
Enoblituzumab
T9901A-002
Synonym: MGA271,TJ-271
Target: Others
EGFR-IN-8
T11162
Synonym:
Target: EGFR, c-Met/HGFR
EGFR-IN-99
T35901
Synonym: JBJ-03-142-02
Target: EGFR, HER
EMI1
T61016
Synonym:
Target: EGFR
BLU-945
T9754
Synonym: BLU945,BLU 945
Target: EGFR
Vibostolimab (anti-TIGIT)
T35391
Synonym: Vibostolimab (anti-TIGIT)
Target: Others
MRT-2359
T67934
Synonym:
Target: Others
Nidanilimab
T76873
Synonym: CAN04
Target: IL Receptor
Sapitinib
T6092
Synonym: AZD-8931
Target: EGFR
NT157
T4605
Synonym:
Target: IGF-1R, STAT
CDK9-IN-7
T10745
Synonym:
Target: CDK
LCS3
T60446
Synonym:
Target: Apoptosis, Glutathione reductase
1 2 3
Cat No. Product Name Synonyms Targets
TN2108 Protohypericin Others
Protohypericin, a naphthodianthrone derivative found in the plant Hypericum perforatum, exhibits photocytotoxicity and is utilized in tumor necrosis targeted radiotherapy through its radioiodinated form.
T4903 Heptadecanoic acid Others , Endogenous Metabolite
Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many "odd" length long chain amino acids are derived from the consumption of dairy fats (milk and meat). Heptadecanoic acid constitutes 0.61% o...
TN1153 Polyporenic acid C Apoptosis , PARP , Caspase , PI3K
Polyporenic acid C shows inhibitory activity against human collagenase.
T34394 Rotenolone Rotenolone I,12alpha-HYDROXYROTENONE Others
Rotenolone (12alpha-HYDROXYROTENONE) is a metabolite of Rotenone which is a natural compound derived from plants of the genera Derris and Lonchocarpus.
T3S0153 Xanthatin Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial
1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr...
TN3972 Epimedokoreanin B Apoptosis , Others , Antibacterial
Epimedokoreanin B (EKB), an isoprenylated flavonoid isolated from Korean Epimedium, exhibited anticancer activity in human non-small cell lung cancer (NSCLC) A549 and NCI-H292 cells.Epimedokoreanin B also possesses anti-...
T81132 Soladulcoside A
Soladulcoside A, a steroidal glycoside with antineoplastic properties, is derived from the entire Solanum nigrum plant. It demonstrates inhibitory effects on A549 cells, suggesting its applicability in researching non-sm...
TN1642 Ferruginol BCL , PARP , Caspase
Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce apoptosis in non-small cell lung cancer (NSCLC) cells.
T35895 Ingenol 3,20-dibenzoate
Ingenol 3,20-dibenzoate is a powerful activator of protein kinase C (PKC) isoforms. It effectively induces the translocation of nPKC-delta, -epsilon, and -theta as well as PKC-mu from the cytosolic fraction to the partic...
TN3525 Boehmenan ERK , Phosphatase , EGFR , PARP , MEK , Wnt/beta-catenin , Akt , Caspase , STAT , p53
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotox...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00949 VEGFR3/FLT4 Protein, Human, Recombinant (His) Human HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-03958 TGF alpha Protein, Human, Recombinant Human E. coli
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPY-00476 ITGB1 Protein, Human, Recombinant (His) Human HEK293
ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involv...
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His) Mouse HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-04985 TMPRSS11D Protein, Human, Recombinant (His) Human HEK293
TMPRSS11D (HAT) belongs to the large type II transmembrane serine protease (TTSP) family, participating in various biological and physiological processes. TMPRSS11D protein expression in tumorous tissues were correlated ...
TMPY-02259 FKBP25/FKBP3 Protein, Human, Recombinant (GST) Human E. coli
FKBP3 is a member of FK506-binding proteins (FKBPs). miR-145-5p overexpression suppressed cell proliferation of NSCLC cells which was abrogated by FKBP3 overexpression, that FKBP3/Sp1/HDAC2/p27 control cell proliferation...
TMPK-00339 ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293
Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPK-00341 ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPK-01034 SEMA4B Protein, Mouse, Recombinant (His) Mouse HEK293
Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling p...
TMPK-01143 LRIG1 Protein, Human, Recombinant (His) Human HEK293
The leucine-rich repeats and immunoglobulin-like domains (LRIG)-1 is a tumor suppressor gene that belongs to the LRIG family. LRIG1 expression has prognostic significance in various human cancers. Somatic mutations, whic...
TMPK-00340 ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPY-04375 Casein Kinase 1 alpha Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to theprotein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein k...
TMPK-00513 LRIG1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The leucine-rich repeats and immunoglobulin-like domains (LRIG)-1 is a tumor suppressor gene that belongs to the LRIG family. LRIG1 expression has prognostic significance in various human cancers. Somatic mutations, whic...
TMPY-03795 EIF5A2 Protein, Human, Recombinant (His) Human E. coli
Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted i...
TMPY-01937 VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01069 VEGFR3/FLT4 Protein, Human, Recombinant (hFc) Human HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-00353 LRRC3B Protein, Human, Recombinant (hFc) Human HEK293
LRRC3B expression is downregulated in many kinds of malignant tumors and it is regarded as a tumor inhibition protein. The leucine-rich repeat-containing 3B (LRRC3B) gene is a putative tumor suppressor located on human c...
TMPY-00088 LRRC3B Protein, Human, Recombinant (His) Human HEK293
LRRC3B expression is downregulated in many kinds of malignant tumors and it is regarded as a tumor inhibition protein. The leucine-rich repeat-containing 3B (LRRC3B) gene is a putative tumor suppressor located on human c...
TMPY-06620 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-06250 CCK4/PTK7 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
Protein tyrosine kinase 7 (PTK7) is a highly conserved but catalytically inactive receptor tyrosine kinase in the Wnt signaling pathway. PTK7 regulates various processes in embryonic development and tissue homeostasis. O...
TMPY-06249 CCK4/PTK7 Protein, Human, Recombinant (His) Human HEK293
Protein tyrosine kinase 7 (PTK7) is a highly conserved but catalytically inactive receptor tyrosine kinase in the Wnt signaling pathway. PTK7 regulates various processes in embryonic development and tissue homeostasis. O...
TMPY-03092 REG1A Protein, Rat, Recombinant (hFc) Rat HEK293
Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopa...
TMPY-03684 REG1A Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopa...
TMPY-01335 REG1A Protein, Human, Recombinant (His) Human HEK293
Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopa...
TMPJ-00281 CADM1 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. C...
TMPY-05474 REG1A Protein, Human, Recombinant (His), Biotinylated Human HEK293
Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopa...
TMPY-03639 REG1A Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopa...
TMPY-02399 TRF1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Telomeric repeat binding factor 1 (TRF1), also known as TERF1, the shelterin complex, which modulates the telomere structures. TRF1 protein structure contains a C-terminal Myb motif, a dimerization domain near its N-term...
TMPY-02210 Serpin B9 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
SerpinB9, also known as Cytoplasmic antiproteinase 3, CAP-3, Peptidase inhibitor 9, SERPINB9 and PI-9, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. Serpin-B9 ( CAP-3 / PI-9 ) is the o...
VEGFR3/FLT4 Protein, Human, Recombinant (His)
TMPY-00949
Species: Human
Expression System: HEK293
TGF alpha Protein, Human, Recombinant
TMPY-03958
Species: Human
Expression System: E. coli
ITGB1 Protein, Human, Recombinant (His)
TMPY-00476
Species: Human
Expression System: HEK293
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
TMPY-01936
Species: Mouse
Expression System: HEK293
TMPRSS11D Protein, Human, Recombinant (His)
TMPY-04985
Species: Human
Expression System: HEK293
FKBP25/FKBP3 Protein, Human, Recombinant (GST)
TMPY-02259
Species: Human
Expression System: E. coli
ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00339
Species: Mouse
Expression System: HEK293
ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00341
Species: Human
Expression System: HEK293
SEMA4B Protein, Mouse, Recombinant (His)
TMPK-01034
Species: Mouse
Expression System: HEK293
LRIG1 Protein, Human, Recombinant (His)
TMPK-01143
Species: Human
Expression System: HEK293
ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00340
Species: Human
Expression System: HEK293
Casein Kinase 1 alpha Protein, Human, Recombinant (GST)
TMPY-04375
Species: Human
Expression System: Baculovirus-Insect Cells
LRIG1 Protein, Cynomolgus, Recombinant (His)
TMPK-00513
Species: Cynomolgus
Expression System: HEK293
EIF5A2 Protein, Human, Recombinant (His)
TMPY-03795
Species: Human
Expression System: E. coli
VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)
TMPY-01937
Species: Mouse
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (hFc)
TMPY-01069
Species: Human
Expression System: HEK293
LRRC3B Protein, Human, Recombinant (hFc)
TMPY-00353
Species: Human
Expression System: HEK293
LRRC3B Protein, Human, Recombinant (His)
TMPY-00088
Species: Human
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06620
Species: Human
Expression System: HEK293
CCK4/PTK7 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-06250
Species: Cynomolgus,Rhesus
Expression System: HEK293
CCK4/PTK7 Protein, Human, Recombinant (His)
TMPY-06249
Species: Human
Expression System: HEK293
REG1A Protein, Rat, Recombinant (hFc)
TMPY-03092
Species: Rat
Expression System: HEK293
REG1A Protein, Cynomolgus, Recombinant (hFc)
TMPY-03684
Species: Cynomolgus
Expression System: HEK293
REG1A Protein, Human, Recombinant (His)
TMPY-01335
Species: Human
Expression System: HEK293
CADM1 Protein, Mouse, Recombinant (hFc)
TMPJ-00281
Species: Mouse
Expression System: Human Cells
REG1A Protein, Human, Recombinant (His), Biotinylated
TMPY-05474
Species: Human
Expression System: HEK293
REG1A Protein, Cynomolgus, Recombinant (His)
TMPY-03639
Species: Cynomolgus
Expression System: HEK293
TRF1 Protein, Human, Recombinant (His)
TMPY-02399
Species: Human
Expression System: Baculovirus-Insect Cells
Serpin B9 Protein, Human, Recombinant (His)
TMPY-02210
Species: Human
Expression System: Baculovirus-Insect Cells
Cat No. Product Name
L2190 Anti-Lung Cancer Compound Library

1735 compounds
A unique collection of 1735 compounds with anti-lung cancer therapeutic activity or targeting lung cancer’s major signaling pathways, can be used for anti-lung cancer drug discovery and mechanism study;
TargetMol