Home Tools
Log in
Products Inhibitors Libraries Recombinant Proteins Kits Services Contact Us
Cart
Peptides Monoclonal Antibodies Dye Reagents PROTAC Virtual Screening TargetMol Kits Cell Counting Kit-8 (CCK-8) Inhibitor Cocktails Natural Products Phenols Alkaloids Flavonoids
Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Search Result

Search Results for " abc "

Targets

ABC Wnt/beta-catenin

75

Compounds

11

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T23602 ABC99 ABC 99,ABC-99 Wnt/beta-catenin
ABC99 is a selective irreversible inhibitor of the wnt-deacylating enzyme. ABC99 inhibited NOTUM (IC50: 13 nM). It also showed excellent selectivity across the serine hydrolase family.
T23601 ABC1183 ABC 1183,ABC-1183 GSK-3 , CDK
ABC1183 is a novel diaminothiazole that inhibits GSK3α, GSK3β and CDK9. ABC1183 inhibits the growth of a numerous cancer cell lines by decreasing cell survival by inducing G2/M arrest and through altering GSK3, glycogen ...
T6367 Abacavir sulfate Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen Apoptosis , HIV Protease , Reverse Transcriptase
Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity
T6750 Opaganib ABC294640 S1P Receptor
Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).
T33648 Nestifylline ABC 99,ABC99,ABC-99
Nestifylline is a biochemical.
T80903 Ulviprubart ABC-008
Ulviprubart, an anti-KLRG1 monoclonal antibody (mAb), is utilized in various disease research [1].
T25611 Lanatoside Lantoside,ABC lanatoside complex
Lanatoside is an FDA-approved cardiac glycoside that has been identified as a candidate anti-dengue compound. It has also been found to promote atherosclerosis. It also has anti-tumor activity, inhibiting the growth of c...
T68352 ABC294735
ABC294735 is a dual SK1/SK2 inhibitor with potential anticancer activity.
T38316 ABC34
ABC34 is an inactive control probe for JJH260 , the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). ABC34 demonstrates an IC50 value greater than ...
T16040 Mepazine Pecazine Apoptosis , MALT
Mepazine (Pecazine) is a potent and selective inhibitor of MALT1. Mepazine inhibits GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 μM and 0.42 μM. Mepazine enhances apoptosis and affects the cell viability.
T8596 Ceefourin 1 MRP
Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
T71299 M-25
M-25 is a Smoothened antagonist and inhibitor of the Hedgehog pathway.
T5354 IRAK4-IN-7 CA-4948 IRAK
IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.
T8491 Vorolanib CM082,X-82 VEGFR , PDGFR
Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.
T68135L (Rac)-Sabcomeline HCl sabcomeline HCl(149156-36-5 Free base) AChR
Sabcomeline HCl is an M1 receptor agonist that can be used to study Alzheimer's disease.
T18962 Dabcyl acid, SE Dabcyl, SE Others
Dabcyl acid, SE (Dabcyl, SE) is the amino-reactive form of Dabcyl acid and used to prepare a variety of FRET-based probes that contain Dabcyl acid.
T76844 Abciximab C7E3 Integrin
Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa...
T40303 5-A-RU-PABC-Val-Cit-Fmoc Others
5-A-RU-PABC-Val-Cit-Fmoc is one of the precursors of 5-A-RU, a small molecule mucosal-associated MAIT activator that is a precursor for bacterial synthesis of riboflavin.
T18963 Dabcyl acid DABCYL,Para-methyl red Others
Dabcyl acid (DABCYL) is the original dark fluorescence quencher.
T3503 MC-Val-Cit-PABC-PNP Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate Others , AChR
MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a pr...
T18721 MAC-VC-PABC-ST7612AA1 Others
MAC-VC-PABC-ST7612AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity[1].
T64082 ABC44
ABC44 is a potent inhibitor of serine hydrolase with IC50s of 0.1 μM and 6.5 μM for palmitoyl protein thioesterase 1 (PPT1) in situ and in vitro, respectively. ABC44 can be used to study late infantile neuron-like lipofu...
T77848 Vc-PABC-DM1
vc-PABC-DM1 is a chemical compound utilized for the synthesis of an antibody-drug conjugate (ADC) that incorporates a disulfide linker. This compound is instrumental in investigating serum stability [1].
T78763 ABCB1-IN-1
ABCB1-IN-1 (compound 3) is a potent inhibitor of ABCB1 that promotes cell apoptosis. Featuring 1-benzylimidazole, it exhibits IC50 values of 1.26 μM for Colo205 cells and 2.21 μM for Colo320 cells, respectively [1].
T79877 MTvkPABC-P5
MTvkPABC-P5d, functioning as a TLR7 agonist, serves as an immune stimulant and is utilized in the synthesis of immune-stimulating antibody conjugates (ISACs) [1].
T35615 Dabcyl-YVADAPV-EDANS
Dabcyl YVADAPV EDANS is a fluorescent IL-1β converting enzyme (ICE) substrate that can be used to detect ICE-like protease activity. Dabcyl YVADAPV EDANS detects fluorescence at λex=360 nm, λem=480 nm.
T77822 Mal-PEG8-Val-Ala-PABC
Mal-PEG8-Val-Ala-PABC is a cleavable linker utilized in the synthesis of Tesirine, an agent-linker conjugate for Antibody-Drug Conjugates (ADC) [1].
T81714 N3-PEG8-Phe-Lys-PABC-Gefitinib
N3-PEG8-Phe-Lys-PABC-Gefitinib is an antibody-drug conjugate (ADC) agent-linker complex exhibiting potent antitumor activity. It incorporates the orally active EGFR tyrosine kinase inhibitor Gefitinib, tethered by the cl...
T17816 DBCO-Val-Cit-PABC-PNP Others
DBCO-Val-Cit-PABC-PNP is a cleavable linker for antibody-drug conjugate (ADC) synthesis[1].
T79513 ABCG2-IN-1 BCRP
ABCG2-IN-1 (compound K2), an analog of Ko143, constitutes an orally active inhibitor targeting ABCG2 with an inhibitory concentration (IC50) of 0.13 μM. Demonstrating favorable oral pharmacokinetics in mice, ABCG2-IN-1 s...
T40342 MC-VC-PABC-amide-PEG1-CH2-CC-885 MC-VC-PABC-amide-PEG1-CH2-CC-885
MC-VC-PABC-amide-PEG1-CH2-CC-885 is an Antibody-Drug Conjugate (ADC) utilizing a protein-degrading agent (protac molecular glue, etc.).
T18875 (Ac)Phe-Lys(Alloc)-PABC-PNP Others
'(Ac)Phe-Lys(Alloc)-PABC-PNP serves as a valuable cleavable linker in the development of antibody-drug conjugates.'
T18331 MC-VC-PABC-DNA31 Others
MC-VC-PABC-DNA31 is a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC) that demonstrates potent antitumor activity. It employs DNA31, an effective inhibitor of RNA polymerase, connected through the MC-VC...
T17351 Acetylene-linker-Val-Cit-PABC-MMAE LCB14-0602 Others
Acetylene-linker-Val-Cit-PABC-MMAE (LCB14-0602) is a drug-linker conjugate for antibody-drug conjugates (ADCs) that combines the ADC linker (Acetylene-linker-Val-Cit-PABC) with the potent tubulin inhibitor MMAE.
T18332 MC-VC-PABC-Aur0101 Others
MC-VC-PABC-Aur0101 is a potent anticancer drug-linker conjugate designed for Antibody-Drug Conjugates (ADCs), comprising Aur0101, an auristatin microtubule inhibitor, connected through the MC-VC-PABC linker to enhance an...
T17357 AcLys-PABC-VC-Aur0101 Others
AcLys-PABC-VC-Aur0101 is a drug-linker conjugate for anti-CXCR4 ADC with potent antitumor activity, comprising the auristatin microtubule inhibitor Aur0101, connected through the cleavable linker AcLys-PABC-VC[1].
T80128 RE(EDANS)EVNLDAEFK(DABCYL)R Beta-Secretase
RE (EDANS) EVNLDAEFK (DABCYL) R is a double-labeled peptide with EDANS and DABCYL, functioning as a fluorescent substrate for BACE1 with an emission wavelength of 360 nm and an excitation wavelength of 528 nm. Its utilit...
T68135 Sabcomeline SB-202026,SB-202026 ; Memric,Memric
Sabcomeline, a potent and functionally selective partial agonist at muscarinic M1 receptors, enhances cognition and is utilized in Alzheimer's disease research [1] [2].
T75369 DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye utilized as a fluorogenic substrate for aspartyl proteinase from the human malaria parasite [1]. It requires protection from light during storage.
T77849 Val-Ala-PABC-Exatecan
Val-Ala-PABC-Exatecan is a Drug-Linker Conjugate for Antibody-Drug Conjugate (ADC) synthesis, comprising a cleavable Tesirine linker (Val-Ala-PABC) and the topoisomerase I inhibitor Exatecan. It is utilized in the constr...
T18754 TCO-PEG1-Val-Cit-PABC-OH Others
TCO-PEG1-Val-Cit-PABC-OH, a cleavable 1-unit PEG ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T28654 Sabcomeline hydrochloride BCI224,BRL-55473,BCI-224,CEB-2424,SB-202026A,Sabcomeline HCl
Sabcomeline is a selective M1 receptor partial agonist.
T17528 BCN-PEG1-Val-Cit-PABC-OH Others
BCN-PEG1-Val-Cit-PABC-OH is a cleavable 1-unit PEG linker specifically utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
T17945 Fmoc-Ala-Ala-Asn-PABC-PNP Others
Fmoc-Ala-Ala-Asn-PABC-PNP is a peptide cleavable ADC linker[1].
T81832 MC-VC-PABC-C6-alpha-Amanitin
MC-VC-PABC-C6-alpha-Amanitin is an antibody-drug conjugate that combines the anticancer toxin alpha-Amanitin with the monoclonal antibody MC-VC-PABC-C6. Alpha-Amanitin acts as a potent inhibitor of RNA polymerase IIα, en...
T68135L1 (Rac)-Sabcomeline
T18268 Mal-PEG1-Val-Cit-PABC-OH Others
Mal-PEG1-Val-Cit-PABC-OH is a 1 unit polyethylene glycol (PEG) ADC linker that possesses cleavable properties. This linker, commonly utilized in the synthesis of antibody-drug conjugates (ADCs), serves as a critical comp...
T81753 Mp-dLAE-PABC-MMAE
mp-dLAE-PABC-MMAE is an agent-linker conjugate for antibody-drug conjugates (ADCs) that incorporates the potent tubulin inhibitor Monomethyl auristatin E (MMAE). This compound is utilized in the synthesis of ADCs to deli...
T79514 ABCG2-IN-2 BCRP
ABCG2-IN-2 is a potent inhibitor of ABCG2, exhibiting favorable oral pharmacokinetic profiles in mice, and is applicable for investigating tumor multidrug resistance (MDR) and erythropoietic protoporphyria (EPP) [1].
T18737 AcLysValCit-PABC-DMAE-SW-163D Others
AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugate for antibody-drug conjugates (ADCs), featuring a natural bis-intercalator, SW-163D, attached through an AcLysValCitPABC-DMAE linker[1].

Compounds

ABC99
T23602
Synonym: ABC 99,ABC-99
Target: Wnt/beta-catenin
ABC1183
T23601
Synonym: ABC 1183,ABC-1183
Target: GSK-3, CDK
Abacavir sulfate
T6367
Synonym: Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen
Target: Apoptosis, HIV Protease, Reverse Transcriptase
Opaganib
T6750
Synonym: ABC294640
Target: S1P Receptor
Nestifylline
T33648
Synonym: ABC 99,ABC99,ABC-99
Target:
Ulviprubart
T80903
Synonym: ABC-008
Target:
Lanatoside
T25611
Synonym: Lantoside,ABC lanatoside complex
Target:
ABC294735
T68352
Synonym:
Target:
ABC34
T38316
Synonym:
Target:
Mepazine
T16040
Synonym: Pecazine
Target: Apoptosis, MALT
Ceefourin 1
T8596
Synonym:
Target: MRP
M-25
T71299
Synonym:
Target:
IRAK4-IN-7
T5354
Synonym: CA-4948
Target: IRAK
Vorolanib
T8491
Synonym: CM082,X-82
Target: VEGFR, PDGFR
(Rac)-Sabcomeline HCl
T68135L
Synonym: sabcomeline HCl(149156-36-5 Free base)
Target: AChR
Dabcyl acid, SE
T18962
Synonym: Dabcyl, SE
Target: Others
Abciximab
T76844
Synonym: C7E3
Target: Integrin
5-A-RU-PABC-Val-Cit-Fmoc
T40303
Synonym:
Target: Others
Dabcyl acid
T18963
Synonym: DABCYL,Para-methyl red
Target: Others
MC-Val-Cit-PABC-PNP
T3503
Synonym: Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate
Target: Others, AChR
MAC-VC-PABC-ST7612AA1
T18721
Synonym:
Target: Others
ABC44
T64082
Synonym:
Target:
vc-PABC-DM1
T77848
Synonym:
Target:
ABCB1-IN-1
T78763
Synonym:
Target:
MTvkPABC-P5
T79877
Synonym:
Target:
Dabcyl-YVADAPV-EDANS
T35615
Synonym:
Target:
Mal-PEG8-Val-Ala-PABC
T77822
Synonym:
Target:
N3-PEG8-Phe-Lys-PABC-Gefitinib
T81714
Synonym:
Target:
DBCO-Val-Cit-PABC-PNP
T17816
Synonym:
Target: Others
ABCG2-IN-1
T79513
Synonym:
Target: BCRP
MC-VC-PABC-amide-PEG1-CH2-CC-885
T40342
Synonym: MC-VC-PABC-amide-PEG1-CH2-CC-885
Target:
(Ac)Phe-Lys(Alloc)-PABC-PNP
T18875
Synonym:
Target: Others
MC-VC-PABC-DNA31
T18331
Synonym:
Target: Others
Acetylene-linker-Val-Cit-PABC-MMAE
T17351
Synonym: LCB14-0602
Target: Others
MC-VC-PABC-Aur0101
T18332
Synonym:
Target: Others
AcLys-PABC-VC-Aur0101
T17357
Synonym:
Target: Others
RE(EDANS)EVNLDAEFK(DABCYL)R
T80128
Synonym:
Target: Beta-Secretase
sabcomeline
T68135
Synonym: SB-202026,SB-202026 ; Memric,Memric
Target:
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS
T75369
Synonym:
Target:
Val-Ala-PABC-Exatecan
T77849
Synonym:
Target:
TCO-PEG1-Val-Cit-PABC-OH
T18754
Synonym:
Target: Others
Sabcomeline hydrochloride
T28654
Synonym: BCI224,BRL-55473,BCI-224,CEB-2424,SB-202026A,Sabcomeline HCl
Target:
BCN-PEG1-Val-Cit-PABC-OH
T17528
Synonym:
Target: Others
Fmoc-Ala-Ala-Asn-PABC-PNP
T17945
Synonym:
Target: Others
MC-VC-PABC-C6-alpha-Amanitin
T81832
Synonym:
Target:
(Rac)-Sabcomeline
T68135L1
Synonym:
Target:
Mal-PEG1-Val-Cit-PABC-OH
T18268
Synonym:
Target: Others
mp-dLAE-PABC-MMAE
T81753
Synonym:
Target:
ABCG2-IN-2
T79514
Synonym:
Target: BCRP
AcLysValCit-PABC-DMAE-SW-163D
T18737
Synonym:
Target: Others
1 2

Recombinant Proteins

Species：
Human (5)
E. coli (2)
Halobacterium salinarum (2)
Rickettsia typhi (1)
Streptococcus pneumoniae (1)
Expression System：
E. coli (9)
HEK293 (1)
in vitro E. coli expression system (1)
Tag：
N-terminal 10xHis-tagged and C-terminal Myc-tagged (3)
N-terminal 6xHis-tagged (2)
C-terminal 10xHis-tagged (1)
His (1)
N-Trx (1)
N-terminal 10xHis-tagged (1)
N-terminal 6xHis-SUMO-tagged (1)
Tag-Free (1)
Cat No. Product Name Species Expression System
TMPH-01711 ABCC1 Protein, Human, Recombinant (His) Human E. coli
Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs a...
TMPH-00970 ABCD1 Protein, Human, Recombinant (His) Human in vitro E. coli expression system
ABCD1 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system.
TMPH-00981 ABCB1 Protein, Human, Recombinant (His) Human E. coli
ABCB1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-01145 ABCB5 Protein, Human, Recombinant (Trx) Human E. coli
ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progen...
TMPH-03414 RT0041 Protein, Rickettsia typhi, Recombinant (His & Myc) Rickettsia typhi E. coli
Could be part of an ABC transporter complex.
TMPH-03591 PsaA Protein, S. pneumoniae, Recombinant (His & Myc) Streptococcus pneumoniae E. coli
Part of an ABC transporter complex involved in manganese import.
TMPH-00628 GltI/YbeJ Protein, E. coli, Recombinant (His & SUMO) E. coli E. coli
Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate.
TMPH-00652 MMBP Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins such as maltotriose.
TMPH-00786 BtuD Protein, Halobacterium salinarum, Recombinant (His) Halobacterium salinarum E. coli
Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system.
TMPH-00787 BtuD Protein, Halobacterium salinarum, Recombinant Halobacterium salinarum E. coli
Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system.
TMPY-02549 GBP1 Protein, Human, Recombinant (His) Human HEK293
Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 ex...
CORPORATE
About Us Careers Privacy Notice Events & News Terms & Conditions
SUPPORT
Contact Us Worldwide Distributors Quality Control Technical Support
RESOURCE
Product Catalog Product Citations Signaling Pathways Solution Calculators
FOLLOW OUR
Social Network
Newsletter Subscription
Subscribe to receive our lastest product updates and special offers!
Corporate
Support
Resource
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
TargetMol
Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved.