6-aminopurine hydrochloride

Adenine hydrochloride is a purine nucleobase and a chemical component of DNA and RNA. It is involved in cellular respiration, protein synthesis, and plays an important role in energy metabolism through high-energy molecules such as ATP, NAD, and FAD. It can be used to induce hyperuricemia and chronic kidney injury models.

Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).

Adenine-15N5 hydrochloride hydrate is a tritium-labeled form of adenine. Adenine (6-Aminopurine), a purine, serves as one of the four nucleotide bases in DNA. It is an essential component in DNA and RNA, playing a crucial role in cellular respiration, the formation of ATP, and coenzymes NAD and FAD, as well as in protein synthesis.