11-beta

11-Beta-hydroxyandrostenedione (NSC-17102) is a steroid mainly found in the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue), which is a 11β-hydroxysteroid dehydrogenase isozymes inhibitor. Measuring plasma 11-Beta-hydroxyandrostenedione can distinguish the adrenal or ovarian origin of hyperandrogenism with 4-androstenedione increases.

Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stress responses in the body.

11Beta-hydroxyprogesterone (11β-Hydroxyprogesterone) is an inhibitor of 11beta-hydroxysteroid dehydrogenase (11betaHSD) type 2, which activates the human hydrocorticosteroid receptor in COS-7 cells, and may be useful in the study of metabolism-related diseases.

11Beta-hydroxyprogesterone (Standard) is a reference standard for research and analysis in studies involving 11Beta-hydroxyprogesterone. 11Beta-hydroxyprogesterone (11β-Hydroxyprogesterone) is an inhibitor of 11beta-hydroxysteroid dehydrogenase (11betaHSD) type 2, which activates the human hydrocorticosteroid receptor in COS-7 cells, and may be useful in the study of metabolism-related diseases.

11beta-Hydroxylupeol is a natural product for research related to life sciences. The catalog number is TN2592 and the CAS number is 49776-92-3.

ent-11β-Hydroxyatis-16-ene-3,14-dione, identified by catalog number TN3933 and CAS number 1092103-22-4, is a natural product used for research in life sciences.

11β,13-Dihydrotaraxinic acid is a naturally occurring small-molecule metabolite that has been identified as a bioactive compound suitable for use in life science and biochemical research applications.11β,13-Dihydrotaraxinic acid is primarily utilized as a reference or research-grade material for studies involving natural product chemistry, metabolic pathway analysis, bioactivity screening, and experimental validation in pharmacological, biochemical, or molecular biology contexts where structurally defined plant-derived compounds are required.

Emodin (Frangula emodin) is an 11β-HSD1 inhibitor with a selective IC50 of 186 and 86 nM against 11β-HSD1 in humans and mice, respectively. Emodin has antiviral, anti-inflammatory, and anti-cancer effects. Emodin can improve metabolic disorders in diet-induced obese mice.

11,13-Dihydrolactucin is a natural sesquiterpene lactone applicable for biochemical experiments and drug synthesis research.

11β-Hydroxyandrosterone is a urinary adrenal-derived androgen metabolite in children with CAH.

Carbenoxolone (Biogastrone) is an inhibitor of 11β-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents the development of fatty liver disease.

11β-Hydroxy-17α-methyltestosterone is a metabolite of 17α-methyltestosterone.

11β,13-Dihydrolactucopicrin is a terpenoid isolated from chicory exhibiting inhibitory activity against yeast α-glucosidase (IC50=42.49 µM).

Eurycomanol 2-O-β-D-glucopyranoside, a natural diterpenoid compound, is extracted from Tongkat Ali.

11-Beta-hydroxyandrostenedione (Standard) is a reference standard for research and analysis in studies involving 11-Beta-hydroxyandrostenedione. 11-Beta-hydroxyandrostenedione (NSC-17102) is a steroid mainly found in the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue), which is a 11β-hydroxysteroid dehydrogenase isozymes inhibitor. Measuring plasma 11-Beta-hydroxyandrostenedione can distinguish the adrenal or ovarian origin of hyperandrogenism with 4-androstenedione increases.

Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.

Diammonium Glycyrrhizinate (Glycyrrhizin) , an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-β-hydroxysteroid dehydrogenase and other enzymes involved in the metabolism of corticosteroids. Therefore, glycyrrhizic acid, the main and sweet component of licorice, has been studied for its ability to cause hypermineralocorticoidism with potassium loss and sodium retention, edema, increased blood pressure, as well as inhibited the renin-angiotensin-aldosterone system.

11β-Hydroxycedrelone has cytotoxic activity, it exhibits moderate inhibitory activity against HL-60 cell line with the IC50 values of 8.9 uM.

1→4-β-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B, a component of the plant Poria cocos, is identified as 3-O-β-Allopyranosyl-(1→4).

Tricosanoic acid (Tricosan-1-oic acid) , also known as N-tricosanoate or tricosylate, belongs to the class of organic compounds known as very long-chain fatty acids.Tricosanoic acid has been detected in multiple biofluids, such as blood and urine. Within the cell, Tricosanoic acid is primarily located in the membrane (predicted from logP), cytoplasm and adiposome. Tricosanoic acid is also a parent compound for other transformation products, including but not limited to, beta-D-galactosyl-N-(tricosanoyl)sphingosine, beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11)-N-tricosanoylsphingosine, and N-(tricosanoyl)-[(4E,6E)-tetradecasphingadienine]-1-phosphoethanolamine. Outside of the human body, Tricosanoic acid can be found in citrus, date, and papaya. This makes Tricosanoic acid a potential biomarker for the consumption of these food products.

AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2.

AKBA (Standard) is a reference standard for research and analysis in studies involving AKBA. AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2.

11-Keto-beta-boswellic acid (Standard) is a reference standard for research and analysis in studies involving 11-Keto-beta-boswellic acid. 11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose dependent cardioprotective effect manifested by dose-dependent reduction in serum lactate dehydrogenase

11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose dependent cardioprotective effect manifested by dose-dependent reduction in serum lactate dehydrogenase