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Results for "
γ-glutamylcysteine synthetase
" in TargetMol Product Catalog- Inhibitors & Agonists4
- Recombinant Protein1
L-BUTHIONINE-(S,R)-SULFOXIMINE
L-Butionine sulfoximine
T537183730-53-4
L-Buthionine-(S,R)-sulfoximine, a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM), induces oxidative stress in cells by depleting GSH.
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γ-Glu-Cys (ammonium salt)
T35454
γ-Glu-Cys is an intermediate in glutathione (GSH) synthesis.1It is formed by ATP-dependent condensation of cysteine and glutamate by γ-glutamylcysteine synthetase. γ-Glu-Cys is also an essential component of phytochelatins, the heavy metal detoxifying enzymes in plants.2
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DL-Buthionine-(S,R)-sulfoximine
NSC 381100, D,L-Buthionine-(S,R)-sulfoximine, Butionine sulfoximine
T77085072-26-4
DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase used for the treatment of solid tumors.
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L-Buthionine-(S,R)-sulfoximine hydrochloride
T60407
L-Buthionine-(S,R)-sulfoximine hydrochloride is a potent, cell-permeable, fast-acting, irreversible inhibitor of G-glutamylcysteine synthetase (γ-GCS) that depletes cellular glutathione levels. It has IC50s of 1.9 μM, 8.6 μM, and 29 μM in melanoma, breast, and ovarian tumor specimens, respectively [1] [2].
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