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Natural Product Categories Natural Product Categories Saxifragales
Saxifragales is an order of flowering plants that includes families such as Saxifragaceae, Crassulaceae, and Hamamelidaceae, encompassing diverse ecological forms from succulents to woody shrubs. Members of Saxifragales produce a wide range of secondary metabolites including flavonoids, tannins, phenolic acids, and triterpenoids. In biomedical research, Saxifragales is important for its anti-inflammatory, antioxidant, hepatoprotective, and wound-healing properties, particularly from medicinal genera like Rhodiola and Hamamelis. The order is also significant for studying adaptation to extreme environments, including alpine and arid habitats, and for understanding metabolite evolution in early eudicots.
- BenzoyloxypaeoniflorinBenzoyloxypeoniflorinT4S165872896-40-3Benzoyloxypaeoniflorin (Benzoyloxypeoniflorin) is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation.
- $129
SizeQTY - PaeoniflorinPeoniflorinT223023180-57-6Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.
- $41
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Cited - Thonningianin AT3S0218271579-11-41. Thonningianin A has anti-cancer activities.2. Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor.3. Thonningianin A has antioxidant property, involves radical scavenging, anti-superoxide formation and metal chelation.
- $44
SizeQTY Cited - HamamelitanninTN1722469-32-9Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans and mouse mammary gland infection models. It also has a high protective activity on cell damag
- $98
SizeQTY - Homobutein3-O-Methylbutein, 2',4,4'-Trihydroxy-3-methoxychalconeTN422034000-39-0Homobutein (3-O-Methylbutein) is a dual inhibitor of HDACs and NF-κB with IC50s of 190 and 38 μM. Homobutein is an iron chelator with anticancer, anti-inflammatory, antiparasite, and antioxidation activities.
- $98
SizeQTY - OxypaeoniflorinOxypaeonifloraT377339011-91-1Oxypaeoniflorin a monoterpene glycoside compound isolated from Paeoniae, is an antioxidant, is neuroprotective and anti-inflammatory.
- $50
SizeQTY Cited - AlbiflorinAlibiflorinT6S165339011-90-01. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced reduction of cell viability, nuclear and mitochondrial apoptotic alteration, reactive oxygen species accumulation and B-cell lymphoma 2 (Bcl-2)/Bax ratio. 4. Albiflorin can serve as a new chemical marker for the quality control of Paeoniae Radix and the Chinese Pharmacopoeia can be updated, via has similar anti-inflammatory effects to paeoniflorin.
- $31
SizeQTY - Pinocembrin-7-O-β-D-glucopyranosidePinocembrin 7-O-beta-D-glucosideT571075829-43-5Pinocembrin-7-O-β-D-glucopyranoside (Pinocembrin 7-O-beta-D-glucoside) is a natural product isolated from Penthorum chinense Pursh.
- $30
SizeQTY - Galloylpaeoniflorin6'-O-Galloyl paeoniflorinTN1067122965-41-7Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress. Galloylpaeoniflorin is also an inhibtior of NF-κB and DNA cleavage.
- $136
SizeQTY - Dihydroevocarpine1-methyl-2-tridecylquinolin-4-oneTN109915266-35-0Dihydroevocarpine (1-methyl-2-tridecylquinolin-4-one) induces AML cytotoxicity, apoptosis and G0/G1 blockade, and inhibits tumor growth by inhibiting mTORC1/2 activity and the mTOR pathway in an acute myeloid leukemia (AML) xenograft model.
- $52
SizeQTY - MethoxsalenXanthotoxin, NCI-C55903, 8-MOP, 8-MethoxypsoralenT1548298-81-7Methoxsalen (NCI-C55903) is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effect of methoxsalen is by means of Photosensitizing Activity.
- $29
SizeQTY Cited - AstilbinTaxifolin 3-rhamnoside, Taxifolin 3-O-rhamnoside, Neoisoastilbin, Neoastilbin, IsoastilbinT279429838-67-3Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.
- $44
SizeQTY Cited - EvocarpineTN112115266-38-3Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
- $52
SizeQTY - BenzoylpaeoniflorinT6S165238642-49-81. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.
- $30
SizeQTY Cited - 5-MethoxyPinocembrosideT135141450878-89-35-MethoxyPinocembroside is a flavonoid isolated from the leaves of [Moringa oleifera].
- $142
SizeQTY - PaeonolideT6S165772520-92-4Paeonolide is a phytoglycoside widely found in the roots of plants of the genus Paeonia and is a novel regulator of the core binding factor subunit alpha-1 in bone-forming cells.
- $48
SizeQTY Cited - EvolitrineT8207523-66-0Glycochenodeoxycholic acid sodium salt is a bile salt formed in the liver from deoxycholic acid and glycine that induces apoptosis in hepatocytes. It acts as a detergent, dissolves fats for absorption, and is itself absorbed.
- $81
SizeQTY - ApiopaeonosideT5S1645100291-86-9Apiopaeonoside is a natural product found in the root of Paeonia suffruticosa.
- $30
SizeQTY Cited - Gallic aldehydeT797213677-79-7Gallic aldehyde shows potent antiviral activity against HSV-1.
- $30
SizeQTY - NeosmitilbinNeoastilbinTN197554081-47-9Neosmitilbin (Neoastilbin) may have antioxidant and anti-inflammatory activities, it shows potent inhibition of lens aldose reductase.
- $40
SizeQTY - 2,3-DimethylhydroquinoneTN9215608-43-52,3-Dimethylhydroquinone exhibits inhibitory activity against cancer cells such as MDA-MB-231, HT-29, HT-1080, and HL-60 with an IC50 of 1.6–6.5 μM, and demonstrates antifungal activity against Candida krusei Berkouet.
- $35
SizeQTY - (±)-EvodiamineT75424518-18-3(±)-Evodiamine is an alkaloid isolated from Evodiae fructus and a topoisomerase I inhibitor. It also inhibits adipocyte differentiation and diabetes by downregulating IGF-1/HIF-1α and IL-6/STAT pathways. As an inhibitor of NF-κB activation, it suppresses invasion, promotes apoptosis, and inhibits TNF-induced Akt activation.
- $29
SizeQTY - Lupeol palmitateTN110732214-80-5Lupeol palmitate is a naturally occurring compound that can be extracted from Ligularia songarica and has antiulcer activity and gastrointestinal protection.
- $162
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