Perilla

(-)-Perillaldehyde shows antibacterial activity.

Perillene (3-Isohexenylfuran) is an actiive constituent in the drug which promotes enterocinesia. Perillen demonstrates strong resistance activity against staphylococcus aureus and E.coli.

2-Methylcyclopent-2-enone is a cyclic ketone widely used in biochemical experiments and drug synthesis research.

4,4-Dimethyl-2-cyclopenten-1-one is a natural product derived from Apocyniveneti Folium that exhibits antitumor activity. 4,4-Dimethyl-2-cyclopenten-1-one selectively kills tumor cells (HSC-2, HL-60). The CC50 (50% cytotoxic concentration) values for 4,4-Dimethyl-2-cyclopenten-1-one are 43.8 μg/mL, 152 μg/mL, 118 μg/mL, and 14.0 μg/mL (HSC-2, HSC-3, HSG, HL-60).

Stigmasterol glucoside is a natural sterol and 5α-reductase inhibitor (IC50=27.2 µM) with potential antioxidant and antitumor properties.

S)-(-)-Perillic acid is a terpenoid natural product capable of inhibiting protein pentosylisation and protein acylation. It exhibits anti-infective and anti-cancer activity, inducing cell cycle arrest and apoptosis in non-small cell lung cancer cells while increasing intracellular protein levels of Bax, p21, and caspase-3.

Dehydroperilloxin possesses inhibitory activity against cyclooxygenase-1, with the IC(50) value of 30.4 microM.

Perilloxin possesses measurable inhibitory activity against cyclooxygenase-1 (COX-1), exhibiting an IC50 value of 23.2 μM, and this biochemical property supports its application as a functional research molecule for studying inflammatory signaling pathways, enzyme inhibition mechanisms, and structure–activity relationships relevant to prostaglandin biosynthesis and inflammation-associated biological processes.