Nerium

Oleaside A is isolated from Nerium oleander.

Picein (Piceoside) is derived from Picrorhiza kurroa and shows antioxidant properties.

1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.

Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).

Adynerin is a steroid found in the herbs of Nerium oleander.

Androsin, isolated from Picrorhiza Kurroa Royle ex Benth, has anti-asthmatic effects.

Adynerigenin beta-neritrioside (Adynerin gentiobioside) is a trisaccharide glycoside isolated from oleander leaves.

8-Hydroxydigitoxigenin is a natural product of Nerium, Apocynaceae. The catalog number is TN5291 and the CAS number is 1049674-06-7. 8-Hydroxydigitoxigenin can be used as a reference standard.

Uzarin is a natural product for research related to life sciences. The catalog number is TN5215 and the CAS number is 20231-81-6.

Uzarigenin digitaloside is a natural product for research related to life sciences. The catalog number is TN5214 and the CAS number is 61217-80-9.

Dehydroadynerigenin beta-neritrioside is a natural product for research related to life sciences. The catalog number is TN3793 and the CAS number is 143212-60-6.

β-Anhydrouzarigenin is a natural product of Nerium, Apocynaceae. The catalog number is TN5290 and the CAS number is 3080-20-4. β-Anhydrouzarigenin can be used as a reference standard.

17alpha-Neriifolin and 17alpha-Deacetyltanghinin have little anti-proliferative activity, indicating that the 17beta configuration is critical for the anti-proliferative activity of these compounds.

Neridienone B has significant effects on calcein accumulation. Neridienone exhibits significant leishmanicidal activity against amastigotes of L. mexicana.

Dehydroadynerigenin glucosyldigitaloside is a natural product for research related to life sciences. The catalog number is TN3792 and the CAS number is 144223-70-1.

Dehydroadynerigenin digitaloside is a natural product for research related to life sciences. The catalog number is TN3791 and the CAS number is 52628-62-3.

An antitumor agent containing at least one compound selected from the group consisting of nerigoside, oleandrigenin, sarmentoside, oleaside A, oleandrin, 8β-hydroxy odoroside A, narciclasine, trans-dihydronarciclasine and bisdeoxynarciclasine is provided, this antitumor agent has an advantage of having an excellent therapeutic effect of tumor and less side effects.

Cardenolide B-1 is a natural product of Nerium, Apocynaceae. The catalog number is TN3595 and the CAS number is 1318158-89-2. Cardenolide B-1 can be used as a reference standard.

Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.