Nardostachys

1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the

Nardosinonediol (Tetrahydronardosinon) is a natural compound derived from Nardostachys jatamansi that acts as a serotonin transporter (SERT) inhibitor, regulating serotonin levels and thus exerting antidepressant effects.

Kanshone A, a sesquiterpenoid naturally derived from Nardostachys chinensis, is cytotoxic and inhibits the proliferation of P-388 leukemia cells.

Isonardosinone, a nardosinone-type sesquiterpene from Nardostachys jatamansi, exhibits anti-neuroinflammatory and cytotoxic activities, inhibits NF-B and MAPK-mediated inflammatory pathways, and attenuates ovx-induced osteoclastogenesis and bone loss.

Nardoaristolone B, a nor-sesquiterpenoid with an unusual fused ring system and having protective effects on the injury of neonatal rat cardiomyocytes. The novel mosquito-repellentsynthetic hydrindanesbased on noreremophilanes and nardoaristolone B which s

Kanshone B shows inhibitory activity against LPS-induced NO production with the IC(50) value of 4.6-21.6 uM.

Narchinol B shows inhibitory activity against LPS-induced NO production.

Debilon shows cytotoxic activity against P-388 cells.

Kanshone H is a natural product for research related to life sciences. The catalog number is TN4378 and the CAS number is 1445952-33-9.

Isonardoperoxide shows strong antimalarial activity against Plasmodium falciparum malaria (6.0 × 10-7 M).

Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity against LPS-induced NO production. Desoxo-narchinol A shows cytotoxic activity against P-388 cells.