Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling, thereby suppressing IL-1β-induced chondrocyte inflammation. It exerts anti-inflammatory effects in a rat model of osteoarthritis (OA).
Oleonuezhenide is a natural product from Chinese formula Ligustrum lucidum, exerts neuroprotective effects and also considered as treatment of osteoporosis.
Ligupurpuroside A is a naturally occurring bioactive compound isolated from Ligustrum robustum. Ligupurpuroside A acts as a competitive inhibitor of lipase, thereby reducing lipid breakdown. This natural lipase inhibitor has potential applications in metabolic research, particularly in the study of obesity and lipid metabolism regulation.
Ligustroside is a natural product of phenolic glycosides from olive plants, which has antioxidant and anti-inflammatory activities. Ligustroside can up-regulate the mRNA expression of SIRT1, CREB1 and GPx1 in SH-SY5Y-APP695 cells. At the same time, the production of nitric oxide (NO) was significantly inhibited in RAW264.7 macrophages stimulated by lipopolysaccharide (LPS). Ligustroside has potential application value in cardiovascular and metabolic diseases related research.
Ligupurpuroside B is a natural phenethyl glycoside discovered in Ligustrum robustum, exhibiting antioxidant activity with an IC50 of 80.4 μM against AAPH-induced haemolysis.
4-(2-Hydroxy-1-methoxyethyl)-1,2-benzenediol, a natural product (catalog number: TN3001, CAS number: 577976-26-2), is used for research in life sciences.