Cupressaceae

Hinokiflavone, a novel modulator of pre-mRNA splicing activity both in vitro and in cellulo, inhibits the assembly of the spliceosome, particularly blocking the formation of the B complex. Additionally, it acts as a SUMO protease inhibitor by impeding the activity of sentrin-specific protease 1 (SENP1). Hinokiflavone also demonstrates significant cytotoxicity, including the inhibition of MMP-9.

Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent. Also, Hinokitiol modulates estrogen receptor signaling and inhibits proliferation of human breast cancer cells.

(-)-Cedrene (Alpha-Cedrene) is a sesquiterpene from cedar oil that has anti-leukemia, antibacterial and anti-obesity properties.

Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinapic acid with antioxidant role protects cardiac cells and its functions from I/R induced oxidative stress. Sinapic acid is a potentially useful agent for the protection against liver fibrosis and cirrhosis. Sinapic acid prevents the alterations in the levels of lipids and lipoproteins by virtue of its anti-lipidaemic effect in isoproterenol induced myocardial infarcted rats. Sinapic acid ameliorates hyperglycemia through PLC-PKC signals to enhance the glucose utilization in diabetic rats.

Cedrene (AI3-51328), a type sesquiterpene compound derived from Xylaria guizhouensis NJAU4742, promotes lateral root formation in plants and acts through growth hormone transport and signaling.

3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) is a predicted metabolite generated by BioTransformer1 from the metabolism of 3-(2,4-dihydroxyphenyl)prop-2-enoic acid. It is produced by the abkar1 enzyme via a reduction-of-alpha-beta-unsaturated-compounds-pattern1 reaction in human gut microbiota.

Cinnamyl 3-methylbutanoate is an unsaturated ester widely used in biochemical experiments and drug synthesis research.

Methyl 3-(2,4-dihydroxyphenyl)propionate is a novel vitamin E derivative that inhibits tyrosinase, which is an antioxidant and inhibits UV-B-induced hyperpigmentation, with potential whitening effects.

(+)-2-Carene is a natural product and a stereoisomer of 2-carene, and can be used in related research in the life sciences.

Junipediol B 8-O-glucoside is a phenylpropane extracted from the above-ground parts of Juniperus phoenicea.

8alpha-Hydroxylabda-13(16),14-dien-19-yl p-hydroxycinnamate is a natural product for research related to life sciences. The catalog number is TN3283 and the CAS number is 117254-98-5.

1,7-Diepi-8,15-cedranediol is a natural product for research related to life sciences. The catalog number is TN2516 and the CAS number is 40768-81-8.

Oleuropeic acid 8-O-glucoside is a natural product used in life sciences research (catalog number: TN4706, CAS number: 865887-46-3).

Agatharesinol is localized in the ray parenchyma cells in Sugi heartwood, and differences between the chemical structure of the contents of ray and axial parenchyma cells were also suggested.

Dehydroheliobuphthalmin has significant neuroprotective activities against glutamate- induced neurotoxicity.

ent-8(14),15-pimaradien-3beta-ol (8(14),15-Isopimaradien-3-ol) can induce vascular relaxation. It displays high antibacterial activities (MIC values lower than 10 microg /mL for most pathogens).

7-Oxohinokinin is a natural product of Chamaecyparis, Cupressaceae. The catalog number is TN3249 and the CAS number is 130837-92-2. 7-Oxohinokinin can be used as a reference standard.

Junipediol B shows antioxidation activity.

15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methoxypinusolidic acid suppresses adipocyte differentiation through the inhibition of PPARgamma-dep

Sequirin C can inhibit feeding behavior.

Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic ingredients, as they suppress UVB-induced MMP-1 expression.

Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, and could be used to treat neurodegenerative diseases. Pinusolide attenuates blockade of insulin signaling by enhancing IRS-1 tyrosine phosphorylation by the activating the AMPK pathway, indicates the targeting of AMPK represents a new therapeutic strategy for hyperglycemia-induced insulin resistance and type 2 diabetes.

3,10-Dihydroxy-5,11-dielmenthadiene-4,9-dione is a natural product of Callitris, Cupressaceae. The catalog number is TN2852 and the CAS number is 106623-23-8. 3,10-Dihydroxy-5,11-dielmenthadiene-4,9-dione can be used as a reference standard.

Sequosempervirin B is a natural product from Sequoia sempervirens.