Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regulating the expression levels of adhesion- and invasion-associated genes.
Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation.
Isosaponarin is a natural product with multiple activities. It inhibits the increase in Ca2+ levels induced by 4-aminopyridine in rat synaptosomes without affecting the membrane potential of synaptosomes, while reducing the phosphorylation of PKC, PKCα, SNAP-25, and MARCKS, thereby inhibiting the release of glutamate from vesicles in synaptosomes.
m-Tolualdehyde is a natural aromatic aldehyde exhibiting inhibitory effects against Tyrophagus putrescentiae (Schrank), rendering it suitable for mite control.
Isosaponarin 2''-O-glucoside (Isovitexin-2''-4'-di-O-beta-D-glucoside) is a natural product for research related to life sciences. The catalog number is TN6403 and the CAS number is 63316-27-8.
Segetalin A is a cyclic peptide isolated from the seeds of Vaccaria hispanica; it belongs to the class of naturally occurring cyclic peptides of plant origin and exhibits weak cytotoxicity toward HEK293 cells.