Bignoniaceae

Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevispora CBS 509.92. It also can induc

1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production via modulation of LAP/LIP/CHOP in leukemia cell lines, which could providing a therapeutic strategy for RAS. 3. Oroxylin A inhibits UCP2s triggers the MPTP opening, and promotes the apoptosis in CaCo-2 cells; uncoupling protein 2 plays a key role in mitochondrial apoptotic pathway. 4. Oroxylin A inhibits N1ICD translocating to the nucleus and binding to epithelial-mesenchymal transition-related transcription factor Snail, thus suppressing the invasion and migration of MCF-7 cells. 5. Oroxylin A improves the sensitivity of K562/ADM cells by increasing apoptosis in leukemic cells and decreasing the expression of CXCR4 and PI3K/Akt/NF-κB pathway, and probably served as a most promising agent for CML treatment.

Chrysin (5,7-Dihydroxyflavone) exhibits many biological activities and pharmacological effects, including antioxidant, anti-inflammatory, anticancer, and antiviral activities.

2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg/disc.

Lapachol (CI75490) has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is an inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.

Catalposide is a potent inducer of (HO)-1 isolated from Catalpa ovate G. Don (Bignoniaceae). Catalposide possesses antioxidant, anti-apoptotic, anti-microbial, anti-tumoral, and anti-inflammatory properties.

α-Lapachone has antineoplastic activity, it shows an approximately trypanocidal activity against Trypanosoma cruzi.

Sibiricose A3 is a compound isolated from the roots of Polygala sibirica L. It is used in the study of prostate cancer.

9-Methoxy-alpha-lapachone, a potential EPHX2 (Epoxide Hydrolase 2) inhibitor, also inhibits NF-κB in HepG2 hepatoma cells.

Lup-20(29)-ene-2alpha,3beta-diol is a natural product of Oroxylum, Bignoniaceae. The catalog number is TN4460 and the CAS number is 61448-03-1. Lup-20(29)-ene-2alpha,3beta-diol can be used as a reference standard.

Specioside B is a natural product for research related to life sciences. The catalog number is TN5043 and the CAS number is 126589-95-5.

4,9-Dihydroxy-alpha-lapachone has antitumor-promoting effects, it exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein-Barr virus early antigen (EBV-EA) activation in Raji cells. 4,9-Dihydroxy-alpha-l

6-O-(E)-Feruloyl-glucose has scavenging hydroxyl radical activity.

9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori, it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 microM. It may have anti-inflammatory activity, it exhibits potent inhi

Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.7 cells , with IC50 values of 9.80 microM. Catalpalactone can inhibit dopamine biosynthesis by

Luteolin-3',7-di-O-glucoside has anti-ulcer and antioxidant activities.

Minecoside exhibits potent antioxidant activity.

Arillatose B is a natural product found in the roots of Polygala arillata.

1-Hydroxy-2-prenylnaphthalene is a natural product for research related to life sciences. The catalog number is TN2536 and the CAS number is 16274-34-3.

(-)-Heraclenol shows in vitro anti-plasmodial activity against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum.(-)-Heraclenol has moderate antibacterial and antifungal activities.

Specioside is a natural cycloaromatic glycoside exhibiting binding activity towards recombinant Hsp90α in SPR assays (Kd = 0.026 µM).

Clemomandshuricoside B is a natural product for research related to life sciences. The catalog number is TN6587 and the CAS number is 905294-48-6.

Foliamenthoic acid shows α-glucosidase inhibition.

6'-O-p-Hydroxybenzoylcatalposide is a natural product of Catalpa, Bignoniaceae. The catalog number is TN3189 and the CAS number is 355143-38-3. 6'-O-p-Hydroxybenzoylcatalposide can be used as a reference standard.