Nardosinonediol (Tetrahydronardosinon) is a natural compound derived from Nardostachys jatamansi that acts as a serotonin transporter (SERT) inhibitor, regulating serotonin levels and thus exerting antidepressant effects.
Isonardosinone, a nardosinone-type sesquiterpene from Nardostachys jatamansi, exhibits anti-neuroinflammatory and cytotoxic activities, inhibits NF-B and MAPK-mediated inflammatory pathways, and attenuates ovx-induced osteoclastogenesis and bone loss.
Nardoaristolone B, a nor-sesquiterpenoid with an unusual fused ring system and having protective effects on the injury of neonatal rat cardiomyocytes. The novel mosquito-repellentsynthetic hydrindanesbased on noreremophilanes and nardoaristolone B which s
Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity against LPS-induced NO production. Desoxo-narchinol A shows cytotoxic activity against P-388 cells.