Nicotinamide, a vitamin B3 derivative, is an inhibitor of SIRT1 (IC50=50-180 μM) and SIRT2 (IC50=2 μM). Nicotinamide can be used as a precursor of nicotinamide adenine dinucleotide or NAD+, which can be supplemented by dietary intake and can prevent or treat melanoglossia and pellagra.

Anabasine ((S)-Anabasine) is an alkaloid extracted from tobacco, acting as a full agonist of nicotinic acetylcholine receptors (nAChRs) with insecticidal activity. It depolarizes TE671 cells that endogenously express human myotypic nAChRs.

Nicotine 1'-N-oxide ((1′S,2′S)-Nicotine-1'-oxide) is a derivative of nicotine obtained from tobacco smoke condensate.

(S)-(-)-Anatabine ((-)-Anatabine), an alkaloid present in tobacco, is an NRF2 activator that attenuates ovalbumin-induced asthma through oxidative stress and inflammation mitigation as well as up-regulation of Nrf2 HO-1 signaling in rats, and may be used in the study of autoimmune thyroiditis.

Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of nicotinamide N-oxide to nicotinamide in the liver is xanthine oxidase.

Solanesol (Betulanonaprenol) is a phytochemical present in tobacco leaf. Starting material for synthesis of co-enzyme Q10. Exhibits antiulcer activity.

2-Propionylpyrrole is a pyrrole derivative widely used in biochemical experiments and drug synthesis research.

Delta-hexalactone is a six-membered cyclic lactone widely used in biochemical experiments and drug synthesis research.

N-Methyl-N-propylamine is a secondary amine widely used in biochemical experiments and drug synthesis research.

2-Ethyl-5-methylpyridine is a pyridine derivative widely used in biochemical experiments and drug synthesis research.

2-Ethyl-6-methylphenol is a phenol derivative with antioxidant activity, widely used in biochemical experiments and drug synthesis research.

4-Methyl-1-pentanol exhibits inhibitory activity against SCC-25 cells and NHK cells (normal human keratinocytes), making it useful for cancer research.

Isonicoteine is a structural isomer of pyridine alkaloids and nicotine, widely used in biochemical experiments and drug synthesis research.

2-(Piperidin-2-yl)piperidine is a bipyridine derivative widely used in biochemical experiments and drug synthesis research.

2,2-Dimethylpentanoic acid is a carboxylic acid widely used in biochemical experiments and drug synthesis research.

2,3-Lutidine (2,3-Dimethylpyridine) is a pyridine derivative widely used in biochemical experiments and drug synthesis research.

Cyclopent-4-ene-1,3-dione is a highly reactive cyclic diketone organic compound that has been employed as a key synthetic intermediate in the laboratory synthesis of more complex molecules, including 2-methoxymethylene-Cyclopent-4-ene-1,3-dione and the natural product derivative chrysotrione B (a 2-acylcyclopentene-1,3-dione derivative), Cyclopent-4-ene-1,3-dione was historically used to investigate the influence of sulfhydryl group-specific chemical reagents on the activity of bovine heart phospholipid exchange protein.