Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) shows human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory activity, with IC50 values of 0.83 +/- 0.04 microM and 4.20 +/- 0.19 microM, respectively.

1. Chelerythrine (Broussonpapyrine) may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiproliferative and antitumor effects.

1. Coptisine chloride (NSC-119754) can be absorbed across intestinal epithelial cells, and completely absorbed compounds.

Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.

1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial apoptosis and inflammation by inhibiting the Rho/ROCK pathway. 3. Coptisine is a potential anti-osteosarcoma drug candidate, via exerting a strong anti-osteosarcoma effect with very low toxicity . 4. Coptisine with a high dosage could inhibit cholesterol synthesis via suppressing the HMGCR expression and promoting the use and excretion of cholesterol via up-regulating LDLR and CYP7A1 expression. 5. Coptisine suppresses adhesion, migration and invasion of MDA-MB-231 breast cancer cells in vitro, the down-regulation of MMP-9 in combination with the increase of TIMP-1 possibly contributing to the anti-metastatic function for breast cancer.

Chelidonic acid (Jervaic acid) is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid (Jervaic acid) also shows anti-inflammatory activity.

Stylopine is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity.

1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.

6-Ethoxychelerythrine (Ethoxychelerythrin) has anti-bacterial activity, it exhibited strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).

Norchelerythrine shows significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 ug mL. It exhibits strong antifeeding activity in a concentration-dependant manner with the EC50 of 62.67 ppm.

Norsanguinarine has antifungal activity, it exhibits 100 % inhibition of A. brassicicola and C. maculans at 1000 ppm whereas. It shows significant cytotoxic activities (ED (50) values < 4 microg ml) against P-388, KB16, A549, and HT-29 cell lines.

Chelidimerine is a natural product for research related to life sciences. The catalog number is TN3631 and the CAS number is 39110-99-1.

8-Acetonyldihydrosanguinarine is a natural product

Dihydrocoptisine is a natural product utilised in biochemical experiments and drug synthesis research.

Oxychelerythrine shows high modulatory activity enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold. It also shows antifeeding activities against Tribolium castaneum adults, with the EC50 of 192.32 p