Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine can be used as a microtubule-destabilizing agent for research on the treatment of hematologic cancers, such as leukemia and

Oleanolic acid 28-O-β-D-glucopyranoside (Beta-D-glucopyranosyl oleanolate) is a natural product derived from Hedera nepalensis.

Macranthoside A (Kalopanaxsaponin H) is a triterpenoid glycoside extracted from rehmannia and belongs to the iridoterpenoid synthesis. Macranthoside A has anti-inflammatory, antioxidant, antibacterial and neuroprotective activities, inhibits the production of pro-inflammatory cytokines and inhibits the activation of inflammatory signaling pathways, helps neutralize harmful free radicals, protects cells from oxidative damage, and promotes the survival and growth of neurons. And prevent neuronal cell death caused by oxidative stress or neurotoxic compounds, which has the potential to treat neurodegenerative diseases, cardiovascular diseases and liver damage.

1. β-Hederin has antileishmanial activity. 2. β-Hederin has apoptotic effect on breast cancer cells, it could be a promising candidate for chemotherapy of breast cancer.

Kalopanaxsaponin G is a natural product