zwitterionic

CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins.

HEPES is a zwitterionic sulfonic acid buffering agent, commonly used to uphold a neutral pH of basal medium within cell cultures.HEPES is a potent inducer of lysosome biogenesis.

L-Carnitine hydrochloride ((R)-Carnitine hydrochloride) is a highly polar small zwitterionic molecule that functions as an essential cofactor for mitochondrial β-oxidation. L-Carnitine hydrochloride facilitates the transport of long-chain fatty acyl-CoAs into mitochondria for subsequent degradation via β-oxidation, thereby supporting cellular energy metabolism. L-Carnitine hydrochloride also displays antioxidant activity and can mitigate metabolic imbalances associated with numerous inborn errors of metabolism, positioning it as an important agent in metabolic research.

HEPES Sodium salt is a nonvolatile zwitterionic chemical buffering agent. HEPES Sodium salt is broadly applied in cell culture. HEPES Sodium salt is effective at pH 6.8 to 8.2. HEPES Sodium salt also induces of lysosome biogenesis.

MES (2-Morpholinoethanesulphonic acid) (2-Morpholinoethanesulphonic acid), a zwitterionic buffer, is effective in the pH range of 5.5-7.7. MES, as one of the Good's buffers, is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments.

HEPPSO is an amphoteric ion buffer with a pH range of 7.1-8.5, exhibiting strong binding affinity for copper(II) ions, and is widely used in biochemical experiments.

MES Sodium is a biological buffer commonly used to prepare solutions with a pH range of 5.5–6.7.

CAPSO is a stable zwitterionic biological buffer commonly used to prepare buffers with a pH of 9.0 to 10.5, suitable for biochemical experiments requiring an alkaline environment.

Sulfobetaine-12 (Zwittergent 3-12 Detergent) is a zwitterionic surfactant, dispersant and emulsifier commonly used in industry.

BES is commonly used to prepare zwitterionic buffers with a pH of 6.4–7.8, exhibiting inhibitory activity against TEM1-β-lactamase, and is widely applied in cellular and molecular biology experiments.

BIS-TRIS propane (BTP), a novel multidentate ligand of nickel- and cobalt-based spin clusters, is a metal chelator. BIS-TRIS propane is often used as a zwitterionic buffer for PCR and protein crystallization studies.

HEPBS is a zwitterionic biologic buffer with a pH range of 7.6 to 9.0. HEPBS can be used in cell culture and other cell experiments.

MOPSO sodium is an amphoteric ionic biological buffer with an effective pH range of 6.2 to 7.6, commonly used in cell culture, enzyme activity assays, and protein purification experiments.

BI-9787 is a zwitterionic inhibitor of ketohexokinase (KHK), demonstrating IC50 values of 12 nM for hKHK-A and 12.8 nM for hKHK-C. It exhibits good metabolic stability in rat hepatocytes and favorable pharmacokinetic properties in vivo in rats.

DPCB (16:0 CB) is a zwitterionic lipidoid capable of forming lipid membranes.

1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (T7773) (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation of glycosphingolipid antigens into DPPC-containing liposomes increases the immunogenicity of the antigens in mice.4

ACES, or N-(2-Acetamido)-2-aminoethanesulfonic acid, is a zwitterionic buffer compound. It offers an effective pH range of 6.8-7.2 for various applications.

ZA3-Ep10, a zwitterionic lipid, is utilized in the formulation of lipid nanoparticles for RNA delivery in vivo and non-viral CRISPR/Cas gene editing applications.

DPPC (129Y83) is a zwitterionic glycerophospholipid frequently utilized in the creation of lipid monolayers, bilayers, and liposomes.

SARS-CoV-2 nsp14-IN-4 (Compound 12q) is a selective inhibitor of the SARS-CoV-2 nsp14 methyltransferase with an IC50 of 19 ± 2.5 nM. Lacking a zwitterionic character, it can penetrate cells and is useful in research on COVID-19 and its etiological agent, SARS-CoV-2 [1].

DSPE-PCB is a lipid mixture that combines the properties of DSPE and zwitterionic polycarboxybetaine (PCB), and is suitable for liposome preparation.

DOPE-C8 is a zwitterionic phospholipid derived from DOPE, used to generate lipid nanoparticles (LNPs) for in vivo mRNA delivery.

Sulfobetaine-8 (Anzergent 3-8) is a zwitterionic surfactant containing both positive and negative charged groups within the molecule, exhibiting good surface activity and emulsifying stability. Sulfobetaine-8 (Anzergent 3-8) is commonly used in pharmaceuticals, cosmetics, and personal care applications, and due to its relatively mild nature and antistatic properties, Sulfobetaine-8 (Anzergent 3-8) is widely applied in various cleansing and formulation systems.

MES-D13 is the deuterated form of MES. MES (2-Morpholinoethanesulphonic acid) serves as a zwitterionic buffer with an effective buffering range of pH 5.5-7.0. As a Good's buffer, MES is extensively used in biochemistry and molecular biology experiments, including cell culture, enzyme activity assays, electrophoresis, and protein research.