wilms tumor protein

Expression system: E. coli
Length: 1-449, Full Length
Activity: Not Tested

Wilms tumor protein WT1 Protein, Human, Recombinant (His) is expressed in Yeast. The accession number is P19544.

Expression system: E. coli
Length: 1-449, Full Length
Activity: Not Tested

Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under control of the proximal AOC1 promoter was significantly enhanced by co-transfection of a WT1 expression construct. Binding of WT1 protein to a cis-regulatory element in the AOC1 promoter was confirmed by electrophoretic mobility shift assay and chromatin immunoprecipitation. WT1-dependent control of polyamine breakdown, which is mediated by changes in AOC1 expression, has a role in kidney organogenesis.

Expression system: P. pastoris (Yeast)
Length: 25-91, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-151, Full Length
Activity: Not Tested