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vorsetuzumab

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  • Inhibitors & Agonists
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Vorsetuzumab
SGN-70
T773621165740-62-4
Vorsetuzumab (Anti-Human CD70 Recombinant Antibody) is a monoclonal antibody that targets the CD70 antigen. It exhibits anticancer activity by enhancing macrophage-associated phagocytosis of kidney cancer cells and inhibiting Burkitt lymphoma.
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Vorsetuzumab mafodotin
SGN-75, h1F6-mcMMAF, Anti-TNFSF7 CD27L CD70 Reference Antibody
T9901A-221
Vorsetuzumab mafodotin, a humanized anti-CD70 monoclonal antibody, conjugates with monomethyl auristatin F (MMAF) through Seattle Genetics' proprietary antibody-drug conjugate (ADC) technology. This affinity allows targeting of various solid tumors and cancers such as renal cell carcinoma, pancreatic, ovarian, and lung cancers, alongside multiple myeloma and several forms of non-Hodgkin lymphoma, all of which express CD70.
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