varicella-zoster

Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml).

CF-1743 is an anti-varicella zoster virus nucleoside and inhibits VZV replication. CF-1743 can be used in studies about infection of varicella and herpes zoster.

Valomaciclovir stearate (A-174606. 0) is a nucleoside analog with antiviral activity against varicella-zoster virus (VZV), and has been used in the study of VZV infections.

Netivudine is a potent nucleoside reverse transcriptase inhibitor (NRTIs), a nucleoside analogue with anti-varicella zoster virus activity that can be used to treat human immunodeficiency virus (HIV) infection. Netivudine works by inhibiting reverse transcriptase, which reduces viral load in the body and slows the progression of the disease through its inhibitory effect.

Acyclovir (Aciclovir) is a guanine analog and orally active antiviral agent characterized by a narrow antiviral spectrum, high selectivity, and low toxicity. Acyclovir exhibits activity against HSV-1 (IC50 = 0.85 μM), HSV-2 (IC50 = 0.86 μM), and varicella-zoster virus. Acyclovir can be used for herpesvirus treatment research.

Vidarabine (Adenine Arabinoside) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the VACCINIA VIRUS and varicella zoster virus.

BRL44385 is an effective and selective inhibitor of the replication of HSV-1 and HSV2, Epstein-Barr virus (EBV), and varicella-zoster virus (VZV).

Sorivudine (BV-araU) has antiviral activity against several viruses including varicella zoster virus, herpes simplex type 1 virus, and Epstein-Barr virus by interfering with viral DNA synthesis.

Lobucavir (BMS-180194; SQ 34514) is a nucleoside analogue and an antiviral agent with broad-spectrum activity against various viruses, including HBV, HIV/AIDS, and α, β, and γ herpesviruses (including CMV, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus).

Denotivir (Vratizolin) is an orally active antiviral agent effective against herpes simplex virus (HSV) and varicella-zoster virus (VZV). It inhibits the proliferation of various cancer cells and possesses anti-leukemic properties. Additionally, Denotivir suppresses the production of TNF-α, IL-1, and IL-6, demonstrating immunosuppressive effects.

PNU-183792 is a 4-oxo-1,4-dihydroquinoline that acts as an orally active inhibitor of herpesvirus polymerases (HSV polymerases). It exhibits broad-spectrum antiviral activity, with IC50 values of 0.69 μM for human cytomegalovirus (HCM), 0.37 μM for varicella-zoster virus, and 0.58 μM for herpes simplex virus (HSV) polymerase. PNU-183792 shows no activity against human α, γ, and δ polymerases but inhibits simian varicella virus (SVV), murine cytomegalovirus (MCMV), and rat cytomegalovirus (RCMV).

VA06 is a derivative of QS-21 that maintains strong adjuvant activity while significantly reducing toxicity. It can self-assemble into flexible worm-like micelles with continuous elongated nanostructures, enhancing drug encapsulation. VA06 induces antigen-specific antibody production, boosts the secretion of TNF-α, IFN-γ, and IL-2 in CD4+ and CD8+ T cells, and enhances the expression of immune-related and antiviral-related genes in mature dendritic cells. Without the need for liposomal formulations, VA06 simplifies production and storage processes. It is applicable for research on varicella-zoster virus infections and Mycobacterium tuberculosis infections.

Vidarabine monohydrate is an adenine arabinoside and antiviral agent that inhibits herpes simplex virus (HSV) and varicella-zoster virus, and may be used in the prognosis of chronic hepatitis B.

A 73209 is a nucleoside analog of the oxetanocin family. A-73209 appears to be a potent and selective agent against herpes simplex virus and varicella-zoster virus infections.

Valnivudine, a precursor of CF-1743, is an orally effective and highly effective anti-herpes zoster (HZ) nucleoside analogue, a bicyclic nucleoside analogue (BCNA). Valnivudine has antiviral activity and is highly inhibitory against varicella zoster virus (VZV). Valnivudine is rapidly and widely converted into CF-1743 in the body.

ML-345 is a selective and potent IDE (insulin-degrading enzyme) inhibitor (IC50=188 nM) targeting the cysteine residue Cys819 in IDE, suitable for studying type 2 diabetes and Alzheimer's disease.

Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mL).

Biotin-PEG8-Vidarabine, a PEG-based linker containing the adenosine analog Vidarabine, functions as an antiviral agent effective against herpes simplex and varicella zoster viruses [1].

Biotin-PEG7-C2-S-Vidarabine is a polyethylene glycol (PEG)-based linker featuring Vidarabine, an adenosine analog and antiviral agent effective against herpes simplex and varicella zoster viruses [1].

Biotin-PEG7-C2-NH-Vidarabine-S-CH3 is a polyethylene glycol (PEG)-based linker that includes the adenosine analog Vidarabine, functioning as an antiviral agent against herpes simplex and varicella zoster viruses [1].

BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase. It exhibits outstanding selectivity for varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1) owing to its phosphorylation by the virus-specific thymidine kinase.

6-Methoxypurine arabinoside (Ara-m), a potent inhibitor of the varicella-zoster virus (VZV), exhibits 50% inhibitory concentrations (IC50) between 0.5 and 3 microM across eight VZV strains [1].

Acyclovir-D4 is a deuterated compound of Acyclovir. Acyclovir (T1454) has a CAS number of 59277-89-3. Acyclovir (T1454) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family.

Acyclovir-D4 (Standard) is a reference standard of Acyclovir-D4 intended for quantitative analysis, quality control, and related biochemical research applications. Acyclovir-d4 is a deuterated compound of Acyclovir. Acyclovir has a CAS number of 59277-89-3. Acyclovir is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family.