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unc-4976

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  • Inhibitors & Agonists
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UNC4976
T13255
UNC4976 is a peptidomimetic positive allosteric modulator (PAM) of the CBX7 chromodomain, facilitating its binding to nucleic acids.
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UNC4976 TFA
T73903
UNC4976 TFA, a positive allosteric modulator (PAM) peptidomimetic of the CBX7 chromodomain, promotes binding to nucleic acids. It concurrently inhibits the H3K27me3-specific recruitment of CBX7 to target genes and enhances non-specific interaction with DNA and RNA [1].
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