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By Target- Hydroxylase
- 5-HT Receptor(3)
- Others(3)
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Results for "
tph1
" in TargetMol Product Catalog- Inhibitors & Agonists4
- Recombinant Protein2
- Antibody Products5
Rodatristat ethyl
RVT-1201, RVT-014, KAR5585
T167791673571-51-1
Rodatristat ethyl (KAR5585) is a groundbreaking, orally active, and potent inhibitor of tryptophan hydroxylase 1 (TPH1) that significantly reduces 5-hydroxytryptamine (5-HT) levels and decreases pulmonary arterial hypertension (PAH) at low concentrations.
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Rodatristat
KAR5417
T167801673568-73-4
Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).
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TPH1-IN-1
T79712
TPH1-IN-1 (compound 40) is a xanthine derivative and inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM. It demonstrates robust in vitro activity and liver microsome stability, effectively impeding the adipocyte differentiation of T3-L1 cells [1].
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4-Chloro-L-phenylalanine
L-PCPA, L-4-Chlorophenylalanine
T7822814173-39-8
4-Chloro-L-phenylalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylase (TPH1 and TPH2).
- $46
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