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(7)
By Target- Chloride channel
- Apoptosis(1)
- Calcium Channel(1)
- HIV Protease(1)
- NF-κB(1)
- PKM(1)
- TNF(1)
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Results for "
tmem16a chloride channel
" in TargetMol Product Catalog- Inhibitors & Agonists8
- Natural Products2
Shikonin
Cited
NSC 252844, Isoarnebin 4, C.I. 75535, Anchusa acid, Alkanna Red, (+)-Shikonin
T1125517-89-5
Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.
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Cited(±)-Liquiritigenin
(±)-4',7-Dihydroxyflavanone
T7542969097-97-8
(±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone), a flavonoid extracted from Angelica keiskei, inhibits the calcium-activated chloride channel TMEM16A.(±)-Liquiritigenin induces an increase in apoptosis and an enhancement of caspase3 activity. (±)-Liquiritigenin induces increased apoptosis and enhanced caspase3 activity. (±)-Liquiritigenin is used in breast cancer research.
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