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  • Thrombopoietin Receptor
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thrombopoietinreceptor

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
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    TargetMol | Natural_Products
Butyzamide
T678941110767-45-7In house
Butyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mouse pro B cell line Ba F3. The phosphorylation of JAK2, STAT3, STAT5 and MAPK is induced. Butyzamide has been shown to help increase platelet levels in mouse xenotransplantation trials.
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6-8weeks
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Avatrombopag
YM477, AKR-501, E5501
T7417570406-98-3
Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation differentiation and platelet production.
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4'-O-Glucosylvitexin
glucosylvitexin
T388276135-82-5
4 -O-Glucosylvitexin (glucosylvitexin) inhibits TPO activity.
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TargetMol | Inhibitor Sale
Lusutrombopag
S-888711, Mulpleta
TQ02231110766-97-6
Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.
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