thiophene 2

Thiophene-2 (TP2) is a targeted inhibitor of polyketide synthase 13 (Pks13), specifically designed to disrupt mycolic acid biosynthesis, effectively inducing rapid cell death in mycobacteria. It demonstrates notable anti-tuberculosis activity and exhibits a minimum inhibitory concentration (MIC) value of 1 μM against Mycobacterium tuberculosis.

Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα γ agonist with EC50 of 0.358μM and 1.21μM. Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is the R-isomer of Aleglitazar.

2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.

5-(2-Thioxo-2,3-dihydrothiazol-4-yl)thiophene-2-carboxamide is a useful organic compound for research related to life sciences and the catalog number is T64886.

5-Methyl-2-((2-nitrophenyl)amino)thiophene-3-carbonitrile is a useful organic compound for research related to life sciences. The catalog number is T65362 and the CAS number is 138564-59-7.

2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene is a useful organic compound for research related to life sciences. The catalog number is T66563 and the CAS number is 1034305-17-3.

(R)-5-Chloro-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T67331 and the CAS number is 721401-53-2.

2-(4-Chloro-3-hydroxy-1-butynyl)-5-(1,3-pentadiynyl)thiophene is a natural product from Laggera pterodonta

5-[(1S,2S)-2-[(Cyclopropylmethyl)amino]cyclopropyl]-N-(tetrahydro-2H-pyran-4-yl)thiophene-3-carboxamide hydrochloride is a cyclopropanoid enzyme compound that acts as a lysine-specific demethylase-1 inhibitor for schizophrenia, developmental disorders, and neurodegenerative diseases.

2-Ethylthiophene is an ethyl-containing pyrazine commonly used in flavor preparation, organic synthesis and biochemical experiments.

MFCD01917484 (ETHYL 2-AMINO-4-(4-METHOXYPHENYL)-3-THIOPHENECARBOXYLATE) is a derivative of thiophene that possesses a variety of properties, including the ability to act as a ligand, catalyst and photosensitizer. It has been used as a model compound for biochemical and physiological studies as well as drug discovery and development.

ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.

N-phenylthiophene-2-carboximidamide is a thiophene derivative that functions as an inhibitor of protein tyrosine kinases (PTKs) and a ligand for G protein-coupled receptors (GPCRs).

Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.

2,2':5',2''-Terthiophene (Trithiophene) (α-Terthiophene) is an oligomer of the heterocyclic compound thiophene, used as a building block for the organic semiconductor polythiophene.

DC-S239 (DC-S239) is a selective inhibitor of histone methyltransferase SETD7 (IC50 = 4.59 μM) with anticancer activity.

Benzo[b]thiophene-3-carbonitrile is a useful organic compound for research related to life sciences. The catalog number is T66350 and the CAS number is 24434-84-2.

HCVcc-IN-1, a derivative of benzothiazole-2-thiophene S-glycoside, exhibits low toxicity and antiviral properties [1].

N-(4-Chlorophenyl)-3-(4-oxo-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-3-yl)propanamide is an active chemical compound characterized by a central thiazolidine ring substituted with a thiophene group, a 4-chlorophenyl group, and a propanamide side chain, engaging in various chemical reactions due to its active functional groups.

MFCD01827729 (ETHYL 2-AMINO-4-(4-METHYLPHENYL)-3-THIOPHENECARBOXYLATE), also known as EMTPC, is a derivative of the amino acid thiophene, a heterocyclic aromatic compound. EMTPC has been investigated for its potential as an anti-inflammatory, analgesic and anticonvulsant drug, its potential as an anticancer drug and its ability to modulate the immune system.

InhA-IN-2 directly inhibits InhA and does not require activation by the catalase peroxidase KatG.